概述

  • 产品名称
  • 描述
    兔多克隆抗体to AIFM3
  • 经测试应用
    适用于: WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    16 amino acid synthetic peptide from near the center of Human AIFM3.

  • 阳性对照
    • Human breast tissue; Human brain tissue lysate

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • 存储溶液
    Preservative: 0.02% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab115478 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 67 kDa.
ELISA Use at an assay dependent concentration.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能
    Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.
  • 组织特异性
    Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level).
  • 序列相似性
    Belongs to the FAD-dependent oxidoreductase family.
    Contains 1 Rieske domain.
  • 结构域
    The Rieske domain induces apoptosis.
  • 细胞定位
    Mitochondrion. Does not translocate to the nucleus upon induction of apoptosis.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AIFL antibody
    • Aifm3 antibody
    • AIFM3_HUMAN antibody
    • Apoptosis inducing factor 3 antibody
    • Apoptosis inducing factor like antibody
    • Apoptosis inducing factor like protein antibody
    • Apoptosis inducing factor, mitochondrion associated antibody
    • Apoptosis-inducing factor 3 antibody
    • Apoptosis-inducing factor-like protein antibody
    • FLJ30473 antibody
    • FLJ45137 antibody
    see all

Anti-AIFM3 antibody 图像

  • Lane 1 : Anti-AIFM3 antibody (ab115478) at 1 µg/ml
    Lane 2 : Anti-AIFM3 antibody (ab115478) at 2 µg/ml

    Lane 1 : Human brain tissue lysate
    Lane 2 : Human brain tissue lysate


    Predicted band size : 67 kDa
  • ab115478, at 5µg/ml, staining AIFM3 in formalin-fixed, paraffin-embedded Human breast tissue by Immunohistochemistry, using a biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-AIFM3 antibody (ab115478)参考文献

ab115478 has not yet been referenced specifically in any publications.

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