16 amino acid synthetic peptide from near the center of Human AIFM3.
Human breast tissue; Human brain tissue lysate
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Preservative: 0.02% Sodium azide
Constituent: 99% PBS
Concentration information loading...
Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 67 kDa.
Use at an assay dependent concentration.
Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.
Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level).
Belongs to the FAD-dependent oxidoreductase family.
Contains 1 Rieske domain.
The Rieske domain induces apoptosis.
Mitochondrion. Does not translocate to the nucleus upon induction of apoptosis.
Information by UniProt
Western blot - Anti-AIFM3 antibody (ab115478)
Lane 1 : Anti-AIFM3 antibody (ab115478) at 1 µg/ml Lane 2 : Anti-AIFM3 antibody (ab115478) at 2 µg/ml All lanes : Human brain tissue lysate Predicted band size: 67 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AIFM3 antibody (ab115478)
ab115478, at 5µg/ml, staining AIFM3 in formalin-fixed, paraffin-embedded Human breast tissue by Immunohistochemistry, using a biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
has not yet been referenced specifically in any publications.
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