Anti-AHI1抗体(ab76843)
Key features and details
- Rabbit polyclonal to AHI1
- Suitable for: IHC-Fr, IHC-P, WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-AHI1抗体 -
描述
兔多克隆抗体to AHI1 -
宿主
Rabbit -
经测试应用
适用于: IHC-Fr, IHC-P, WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat -
免疫原
Synthetic peptide derived from the C terminal domain of human AHI1 protein.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
Constituent: Whole serum -
Concentration information loading...
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纯度
Whole antiserum -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab76843于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IHC-Fr |
Use at an assay dependent concentration.
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IHC-P |
Use at an assay dependent concentration.
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WB |
Use at an assay dependent concentration.
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说明 |
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IHC-Fr
Use at an assay dependent concentration. |
IHC-P
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. |
靶标
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组织特异性
Highly expressed in the most primitive normal hematopoietic cells. Expressed in brain, particularly in neurons that give rise to the crossing axons of the corticospinal tract and superior cerebellar peduncles. Expressed in kidney (renal collecting duct cells) (at protein level). -
疾病相关
Defects in AHI1 are the cause of Joubert syndrome type 3 (JBTS3) [MIM:608629]. JBTS is an autosomal recessive disorder presenting with cerebellar ataxia, oculomotor apraxia, hypotonia, neonatal breathing abnormalities and psychomotor delay. Neuroradiologically, it is characterized by cerebellar vermian hypoplasia/aplasia, thickened and reoriented superior cerebellar peduncles, and an abnormally large interpeduncular fossa, giving the appearance of a molar tooth on transaxial slices (molar tooth sign). Additional variable features include retinal dystrophy and renal disease. JBTS3 shows minimal extra central nervous system involvement and appears not to be associated with renal dysfunction. -
序列相似性
Contains 1 SH3 domain.
Contains 7 WD repeats. -
细胞定位
Cytoplasm > cytoskeleton > cilium basal body. Cell junction > adherens junction. - Information by UniProt
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数据库链接
- Entrez Gene: 54806 Human
- Entrez Gene: 52906 Mouse
- Entrez Gene: 308923 Rat
- Omim: 608894 Human
- SwissProt: Q8N157 Human
- SwissProt: Q8K3E5 Mouse
- SwissProt: Q6DTM3 Rat
- Unigene: 386684 Human
see all -
别名
- Abelson helper integration site 1 antibody
- Abelson helper integration site 1 protein homolog antibody
- Abelson helper integration site antibody
see all
数据表及文件
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Datasheet download
文献 (0)
ab76843 尚未被引用在任何文献中。