概述

  • 产品名称Anti-AHCYL1抗体
    参阅全部 AHCYL1 一抗
  • 描述
    小鼠单克隆抗体to AHCYL1
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Recombinant fragment: MSMPDAMPLP GVGEELKQAK EIEDAEKYSF MATVTKAPKK QIQFADDMQE FTKFPTKTGR RSLSRSISQS STDSYSSAAS YTDSSDDEVS PREKQQTNSK G, corresponding to amino acids 1-101 of human AHCYL1 (NP_006612) with a 26 kDa tag.

  • 阳性对照
    • HeLa and PC12 cell lysates; recombinant tagged fragment of human AHCYL1 (the immunogen).

性能

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应用

Our Abpromise guarantee covers the use of ab77638 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 59 kDa.
ELISA Use at an assay dependent dilution.

靶标

  • 组织特异性Expressed in dendritic cells.
  • 通路Amino-acid biosynthesis; L-homocysteine biosynthesis; L-homocysteine from S-adenosyl-L-homocysteine: step 1/1.
  • 序列相似性Belongs to the adenosylhomocysteinase family.
  • 发展阶段Expression increases markedly during activation of blood and skin DC (Langerhans cells), but is diminished in terminally differentiated tonsil DC.
  • 结构域The PEST region is essential for the interaction with ITPR1. The PDZ-binding region is required for maximal interaction with ITPR1 and is also responsible for the IP3-insensitive interaction with ITPR1.
  • 细胞定位Endoplasmic reticulum.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AA409031 antibody
    • AdoHcyase 2 antibody
    • Ahcy-rs3 antibody
    • AHCYL1 antibody
    • DC expressed AHCY like molecule antibody
    • DC-expressed AHCY-like molecule antibody
    • DCAL antibody
    • Dendritic cell expressed AHCY like protein antibody
    • Inositol 1,4,5-trisphosphate receptor-binding protein antibody
    • IP3R binding protein released with inositol 1,4,5-trisphosphate antibody
    • IRBIT antibody
    • PRO0233 antibody
    • Putative adenosylhomocysteinase 2 antibody
    • S adenosyl L homocysteine hydrolase 2 antibody
    • S adenosylhomocysteine hydrolase like 1 antibody
    • S-adenosyl-L-homocysteine hydrolase 2 antibody
    • S-adenosylhomocysteine hydrolase-like protein 1 antibody
    • SAHH2_HUMAN antibody
    • XPVKONA antibody
    see all

Anti-AHCYL1 antibody 图像

  • Anti-AHCYL1 antibody (ab77638) at 1/500 dilution + Recombinant fragment of human AHCYL1 at 0.2 µg

    Secondary
    Goat anti-Mouse IgG (H&L)-HRP at 1/5000 dilution

    Predicted band size : 59 kDa
    Observed band size : 37 kDa (why is the actual band size different from the predicted?)
  • Anti-AHCYL1 antibody (ab77638) at 1/500 dilution + HeLa cell lysate at 25 µg

    Secondary
    Goat anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

    Predicted band size : 59 kDa
    Observed band size : 59 kDa
  • Anti-AHCYL1 antibody (ab77638) at 1/500 dilution + PC12 cell lysate at 25 µg

    Secondary
    Goat anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

    Predicted band size : 59 kDa
    Observed band size : 59 kDa

Anti-AHCYL1 antibody (ab77638)参考文献

ab77638 has not yet been referenced specifically in any publications.

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