Anti-AGXT抗体[AT2T4] (ab95452)

概述

  • 产品名称Anti-AGXT抗体[AT2T4]
    参阅全部 AGXT 一抗
  • 描述
    小鼠单克隆抗体[AT2T4] to AGXT
  • 经测试应用适用于: ELISA, ICC/IFmore details
  • 种属反应性
    与反应: Human
    预测可用于: Marmoset (common), Orangutan
  • 免疫原

    Recombinant fragment: YDWRDIVSYV IDHFDIEIMG GLGPSTGKVL RIGLLGCNAT RENVDRVTEA LRAALQHCPK KKL, corresponding to amino acids 330-392 of Human AGXT, purified from E. coli (NP_000021).

  • 阳性对照
    • Human HeLa cells
  • 常规说明Derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant Human AGXT fragment.

性能

应用

Our Abpromise guarantee covers the use of ab95452 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent dilution.
ICC/IF 1/500 - 1/1000.

靶标

  • 组织特异性Liver.
  • 疾病相关Defects in AGXT are the cause of hyperoxaluria primary type 1 (HP1) [MIM:259900]; also known as primary hyperoxaluria type I (PH1) and oxalosis I. HP1 is a rare autosomal recessive inborn error of glyoxylate metabolism characterized by increased excretion of oxalate and glycolate, and the progressive accumulation of insoluble calcium oxalate in the kidney and urinary tract.
  • 序列相似性Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
  • 细胞定位Peroxisome. Mitochondrion matrix. Except in some HP1 patients where AGT is found in the mitochondrial matrix.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AGT antibody
    • AGT1 antibody
    • Agxt antibody
    • AGXT1 antibody
    • Alanine glyoxylate aminotransferase antibody
    • Alanine glyoxylate aminotransferase3 antibody
    • Alanine--glyoxylate aminotransferase antibody
    • EC 2.6.1.44 antibody
    • EC 2.6.1.51 antibody
    • Hepatic peroxisomal alanine glyoxylate aminotransferase antibody
    • Hepatic peroxisomal alanine:glyoxylate aminotransferase antibody
    • L alanine glyoxylate aminotransferase 1 antibody
    • MS773 antibody
    • PH1 antibody
    • Serine pyruvate aminotransferase antibody
    • Serine--pyruvate aminotransferase antibody
    • Serine--pyruvate aminotransferase, mitochondrial antibody
    • Serine:pyruvate aminotransferase antibody
    • SPAT antibody
    • SPT antibody
    • SPYA_HUMAN antibody
    • TLH6 antibody
    see all

Anti-AGXT antibody [AT2T4] 图像

  • Immunofluorescence of Human HeLa cells stained with PI (Red) and ab95452 (1:500) with Alexa 488 (Green).

Anti-AGXT antibody [AT2T4] (ab95452)参考文献

ab95452 has not yet been referenced specifically in any publications.

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