AGRP肽(120-132) (ab45721)

概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human
    • 序列CRKLGTAMNPCSRT
    • 氨基酸120 to 132

相关产品

技术指标

Our Abpromise guarantee covers the use of ab45721 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-AGRP antibody (ab32882)

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.

常规信息

  • 别名
    • Agouti related neuropeptide
    • Agouti Related Protein Homolog
    • Agouti-related protein
    • Agrp
    • AGRP_HUMAN
    • AGRT
    • ART
    • ASIP2
    see all
  • 功能Plays a role in weight homeostasis. Plays a role in the central control of feeding. Reduces food intake. Inhibits cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Acts primarily on MC3R and MC4R. Has very low activity with MC5R.
  • 组织特异性Expressed primarily in the adrenal gland, subthalamic nucleus, and hypothalamus, with a lower level of expression occurring in testis, lung, and kidney.
  • 疾病相关Genetic variations in AGRP may be a cause of obesity (OBESITY) [MIM:601665]. It is a condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat.
  • 序列相似性Contains 1 agouti domain.
  • 结构域The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin.
  • 细胞定位Secreted. Golgi apparatus lumen.
  • Information by UniProt

AGRP peptide (120-132) (ab45721)参考文献

ab45721 has not yet been referenced specifically in any publications.

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The molecular weight of the AGRP peptide (120-132) (ab45721) is 1537.87 g/mol. This therefore equates to 1537870 mg/mol.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"