概述

  • 产品名称Anti-AGL抗体
    参阅全部 AGL 一抗
  • 描述
    小鼠多克隆抗体to AGL
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length Human AGL protein (NP_000019.2, 1 a.a. ~ 1532 a.a).

  • 阳性对照
    • Human liver lysate. AGL transfected 293T cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab72770 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 175 kDa.

靶标

  • 功能Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.
  • 组织特异性Liver, kidney and lymphoblastoid cells express predominantly isoform 1; whereas muscle and heart express not only isoform 1, but also muscle-specific isoform mRNAs (isoforms 2, 3 and 4). Isoforms 5 and 6 are present in both liver and muscle.
  • 疾病相关Glycogen storage disease 3
  • 序列相似性Belongs to the glycogen debranching enzyme family.
  • 翻译后修饰The N-terminus is blocked.
    Ubiquitinated.
  • 细胞定位Cytoplasm. Under glycogenolytic conditions localizes to the nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 1110061O17Rik antibody
    • 4-1 antibody
    • 4-glucantransferase antibody
    • 6-glucosidase antibody
    • 9430004C13Rik antibody
    • 9630046L06Rik antibody
    • AGL antibody
    • AI850929 antibody
    • Amylo 1 6 glucosidase 4 alpha glucanotransferase antibody
    • Amylo-1 antibody
    • Amylo-alpha-1 antibody
    • C77197 antibody
    • Dextrin 6-alpha-D-glucosidase antibody
    • GDE antibody
    • GDE_HUMAN antibody
    • Glycogen debrancher antibody
    • Glycogen debranching enzyme antibody
    • Glycogen storage disease type III antibody
    • Oligo-1 antibody
    see all

Anti-AGL antibody 图像

  • Anti-AGL antibody (ab72770) at 1 µg/ml + Human liver lysate at 25 µg

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 175 kDa
    Observed band size : 150 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-AGL antibody (ab72770) at 1 µg/ml

    Lane 1 : AGL transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 175 kDa
    Observed band size : 175 kDa

Anti-AGL antibody (ab72770)参考文献

ab72770 has not yet been referenced specifically in any publications.

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