This fast track antibody is not yet fully characterized. It is subject to these terms and conditions

概述

  • 产品名称Anti-AGBL1抗体
    参阅全部 AGBL1 一抗
  • 描述
    山羊多克隆抗体to AGBL1

    This product is a fast track antibody. It has been affinity purified and shows high titre values against the immunizing peptide by ELISA. Read the terms of use »

  • 种属反应性

    预测可用于: Mouse, Rat, Cow, Dog, Human
  • 免疫原

    Synthetic peptide:

    C-RPYQVITARVHPGE

    with a Cysteine residue linker, corresponding to internal sequence amino acids 748-761 of Human AGBL1 (NP_689549.2).

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • 存储溶液pH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: 99% Tris buffered saline, 0.5% BSA
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab121034 is purified from goat serum by ammonium sulphate precipitation, followed by antigen affinity chromatography using the immunizing peptide.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Fast track antibodies constitute a diverse group of products that have been released to accelerate your research, but are not yet fully characterized. They have all been affinity purified and show high titre values against the immunizing peptide (by ELISA). Fast track terms of use

应用 Ab评论 说明
WB Use at an assay dependent concentration. Predicted molecular weight: 1 kDa. Preliminary experiments gave bands at approx 100kDa and 24kDa in HeLa lysates after 0.3µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the bands we observe given the calculated size of 120kDa according to NP_689549.2. Both detected bands were successfully blocked by incubation with the immunizing peptide (and BLAST results with the immunizing peptide sequence did not identify any other proteins to explain the additional bands).

靶标

  • 功能Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5.
  • 序列相似性Belongs to the peptidase M14 family.
  • 细胞定位Cytoplasm > cytosol.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Agbl1 antibody
    • ATP/GTP-binding protein-like 1 antibody
    • Carboxypeptidase 4, cytosolic antibody
    • CBPC4_HUMAN antibody
    • Ccp4 antibody
    • Cytosolic carboxypeptidase 4 antibody
    • D430020F16 antibody
    • EG244071 antibody
    • FLJ32310 antibody
    • MGC149239 antibody
    • Nna1 l1 antibody
    • RGD1560280 antibody
    see all

Anti-AGBL1 antibody (ab121034)参考文献

ab121034 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"