概述

  • 产品名称Anti-AGA抗体
  • 描述
    兔多克隆抗体to AGA
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Guinea pig, Cow, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 138-187 (SMGFINEDLS TTASQALHSD WLARNCQPNY WRNVIPDPSK YCGPYKPPGI) of Human AGA (NP_001165459).

  • 阳性对照
    • Human placenta lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • 存储溶液Constituents: 98% PBS, 2% Sucrose
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab115852 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 37 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Cleaves the GlcNAc-Asn bond which joins oligosaccharides to the peptide of asparagine-linked glycoproteins.
  • 疾病相关Defects in AGA are the cause of aspartylglucosaminuria (AGU) [MIM:208400]. AGU is an inborn lysosomal storage disease. Clinical features of AGU include mild to severe mental retardation manifesting from the age of 2, coarse facial features and mild connective tissue abnormalities. This recessively inherited disease is overrepresented in the Finnish population.
  • 序列相似性Belongs to the Ntn-hydrolase family.
  • 细胞定位Lysosome.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Aga antibody
    • AGU antibody
    • Aspartylglucosaminidase antibody
    • Aspartylglucosylamine deaspartylase antibody
    • Aspartylglycosaminuria antibody
    • ASPG_HUMAN antibody
    • ASRG antibody
    • GA antibody
    • Glycosylasparaginase antibody
    • Glycosylasparaginase beta chain antibody
    • N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase antibody
    • N4 (N acetyl beta glucosaminyl) L asparagine amidase antibody
    • N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase antibody
    see all

Anti-AGA antibody 图像

  • Anti-AGA antibody (ab115852) at 1 µg/ml + Human placenta lysate at 10 µg

    Predicted band size : 37 kDa

Anti-AGA antibody (ab115852)参考文献

ab115852 has not yet been referenced specifically in any publications.

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