概述

  • 产品名称Anti-AF10抗体
    参阅全部 AF10 一抗
  • 描述
    山羊多克隆抗体to AF10
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Rat
    预测可用于: Mouse, Chicken, Human, Xenopus laevis
  • 免疫原

    Synthetic peptide (C-

    RLEDTTARFTNAN

    ) corresponding to internal sequence amino acids 281-293 of Human AF10 (NP_004632.1).

  • 阳性对照
    • Rat testis lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris saline, pH 7.3
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab101719 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab101719 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 109 kDa.

靶标

  • 功能Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA.
  • 组织特异性Expressed abundantly in testis.
  • 疾病相关A chromosomal aberration involving MLLT10 is associated with acute leukemias. Translocation t(10;11)(p12;q23) with KMT2A/MLL1. The result is a rogue activator protein.
    A chromosomal aberration involving MLLT10 is associated with diffuse histiocytic lymphomas. Translocation t(10;11)(p13;q14) with PICALM.
  • 序列相似性Contains 1 C2HC pre-PHD-type zinc finger.
    Contains 2 PHD-type zinc fingers.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AF 10 antibody
    • AF10 antibody
    • AF10_HUMAN antibody
    • ALL 1 fused gene from chromosome 10 antibody
    • ALL1 fused gene from chromosome 10 antibody
    • ALL1-fused gene from chromosome 10 protein antibody
    • DKFZp686E10210 antibody
    • MGC75086 antibody
    • MLLT 10 antibody
    • MLLT10 antibody
    • Myeloid/lymphoid or mixed lineage leukemia (trithorax homolog Drosophila) translocated to 10 antibody
    • Myeloid/lymphoid or mixed lineage leukemia translocated to 10 antibody
    • OTTHUMP00000045273 antibody
    • Protein AF 10 antibody
    • Protein AF-10 antibody
    • Protein AF10 antibody
    • Type I AF10 protein antibody
    see all

Anti-AF10 antibody 图像

  • Anti-AF10 antibody (ab101719) at 1 µg/ml + Rat testis lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 109 kDa
    Observed band size : ~140,~60 kDa (why is the actual band size different from the predicted?)

Anti-AF10 antibody (ab101719)参考文献

ab101719 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab101719.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"