概述

  • 产品名称
  • 描述
    兔多克隆抗体to AdSS 2
  • 经测试应用
    适用于: IHC-P, WB, ICC/IFmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    antigen sequence: KLDGEIIPHI PANQEVLNKV EVQYKTLPGW NTDISNARAF KELPVNAQNY VRFIEDELQI PVKWIGVGKS RESM, corresponding to amino acids 379-452 of Human AdSS 2.

  • 阳性对照
    • Human colon tissue; RT-4 and U-251 MG cell lysates; Human Liver and Tonsil lysates; U-251MG cells

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab121810 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/250 - 1/500.
ICC/IF Use a concentration of 1 - 4 µg/ml. Fixation/Permeabilization: PFA/Triton X-100

靶标

  • 功能
    Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
  • 通路
    Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 1/2.
  • 序列相似性
    Belongs to the adenylosuccinate synthetase family.
  • 细胞定位
    Cytoplasm. Partially associated with particulate fractions.
  • Information by UniProt
  • 数据库链接
  • 别名
    • (Ade(-)H, complement of antibody
    • acidic isozyme antibody
    • ADEH antibody
    • Adenylosuccinate synthetase (Ade(-)H complementing) antibody
    • Adenylosuccinate synthetase acidic isozyme antibody
    • Adenylosuccinate synthetase antibody
    • Adenylosuccinate synthetase isozyme 2 antibody
    • Adenylosuccinate synthetase liver isozyme antibody
    • AdSS 2 antibody
    • ADSS antibody
    • AMPSase 2 antibody
    • IMP--aspartate ligase 2 antibody
    • L-type adenylosuccinate synthetase antibody
    • liver isozyme antibody
    • PURA2_HUMAN antibody
    see all

图片

  • ab121810, at 1/40 dilution, staining AdSS 2 in paraffin-embedded Human colon tissue by Immunohistochemistry.
  • All lanes : Anti-AdSS 2 antibody (ab121810) at 1/250 dilution

    Lane 1 : RT-4 cell lysate
    Lane 2 : U-251 MG cell lysate
    Lane 3 : Human Plasma lysate
    Lane 4 : Human Liver lysate
    Lane 5 : Human Tonsil lysate
  • ab121810, at 4µg/ml, staining AdSS 2 in U-251MG cells by Immunofluorescence.

文献

ab121810 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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