概述

  • 产品名称Anti-ADRM1抗体
    参阅全部 ADRM1 一抗
  • 描述
    兔多克隆抗体to ADRM1
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Chimpanzee, Rhesus monkey, Orangutan
  • 免疫原

    Synthetic peptide corresponding to a region between residues 357 and 407 of Human ADRM1 (NP_008933.2).

  • 阳性对照
    • Human osteosarcoma, ovarian carcinoma and prostate carcinoma tissues; Mouse teratoma tissue.

性能

应用

Our Abpromise guarantee covers the use of ab124645 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining.

靶标

  • 功能Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme UCHL5 at the 26S proteasome and promotes its activity.
  • 序列相似性Belongs to the ADRM1 family.
    Contains 1 PH domain.
  • 结构域The PH domain mediates interactions with PSMD1 and ubiquitin. Preferential binding to the proximal subunit of K48-linked diubiquitin allows UCHL5 access to the distal subunit.
  • 细胞定位Cytoplasm. Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 110 kDa cell membrane glycoprotein antibody
    • adhesion regulating molecule 1 antibody
    • Adhesion-regulating molecule 1 antibody
    • ADRM 1 antibody
    • Adrm1 antibody
    • ADRM1_HUMAN antibody
    • ARM 1 antibody
    • ARM-1 antibody
    • ARM1 antibody
    • Gp110 antibody
    • hRpn13 antibody
    • M(r) 110,000 surface antigen antibody
    • Proteasomal ubiquitin receptor ADRM1 antibody
    • proteasome regulatory particle non ATPase 13 antibody
    • Proteasome regulatory particle non-ATPase 13 antibody
    • Regulatory particle non ATPase 13 antibody
    • Rpn13 antibody
    • Rpn13 homolog antibody
    see all

Anti-ADRM1 antibody 图像

  • ab124645, at 1/250 dilution, staining ADRM1 in formalin-fixed, paraffin-embedded Human prostate carcinoma by Immunohistochemistry with DAB staining.
  • ab124645, at 1/250 dilution, staining ADRM1 in formalin-fixed, paraffin-embedded Mouse teratoma tissue by Immunohistochemistry with DAB staining.

Anti-ADRM1 antibody (ab124645)参考文献

ab124645 has not yet been referenced specifically in any publications.

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