Anti-Adrenomedullin抗体[HTA91a/G2] (ab18093)

概述

  • 产品名称Anti-Adrenomedullin抗体[HTA91a/G2]
    参阅全部 Adrenomedullin 一抗
  • 描述
    小鼠单克隆抗体[HTA91a/G2] to Adrenomedullin
  • 经测试应用适用于: IHC-P, IHC-Frmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Chemically synthesized full length Adrenomedullin.

性能

应用

Our Abpromise guarantee covers the use of ab18093 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use at an assay dependent dilution.
IHC-Fr Use at an assay dependent dilution.

靶标

  • 功能AM and PAMP are potent hypotensive and vasodilatator agents. Numerous actions have been reported most related to the physiologic control of fluid and electrolyte homeostasis. In the kidney, am is diuretic and natriuretic, and both am and pamp inhibit aldosterone secretion by direct adrenal actions. In pituitary gland, both peptides at physiologically relevant doses inhibit basal ACTH secretion. Both peptides appear to act in brain and pituitary gland to facilitate the loss of plasma volume, actions which complement their hypotensive effects in blood vessels.
  • 组织特异性Highest levels found in pheochromocytoma and adrenal medulla. Also found in lung, ventricle and kidney tissues.
  • 序列相似性Belongs to the adrenomedullin family.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Adm antibody
    • ADM precursor antibody
    • ADML_HUMAN antibody
    • AM antibody
    • PAMP antibody
    • Preproadrenomedullin antibody
    • Proadrenomedullin N-20 terminal peptide antibody
    • Proadrenomedullin N20 terminal peptide antibody
    • ProAM N terminal 20 peptide antibody
    • ProAM N-terminal 20 peptide antibody
    • ProAM N20 antibody
    • ProAM-N20 antibody
    • ProAMN20 antibody
    see all

Anti-Adrenomedullin antibody [HTA91a/G2] (ab18093)参考文献

ab18093 has not yet been referenced specifically in any publications.

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