Anti-Adrenomedullin抗体(ab125409)

概述

  • 产品名称Anti-Adrenomedullin抗体
    参阅全部 Adrenomedullin 一抗
  • 描述
    兔多克隆抗体to Adrenomedullin
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Rabbit
  • 免疫原

    Synthetic peptide corresponding to a region within C terminal amino acids 135-184 (VAPRSKISPQ GYGRRRRRSL PEAGPGRTLV SSKPQAHGAP APPSGSAPHF) of Human Adrenomedullin (NP_001115).

  • 阳性对照
    • HepG2 cell lysate.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab125409 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 20 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能AM and PAMP are potent hypotensive and vasodilatator agents. Numerous actions have been reported most related to the physiologic control of fluid and electrolyte homeostasis. In the kidney, am is diuretic and natriuretic, and both am and pamp inhibit aldosterone secretion by direct adrenal actions. In pituitary gland, both peptides at physiologically relevant doses inhibit basal ACTH secretion. Both peptides appear to act in brain and pituitary gland to facilitate the loss of plasma volume, actions which complement their hypotensive effects in blood vessels.
  • 组织特异性Highest levels found in pheochromocytoma and adrenal medulla. Also found in lung, ventricle and kidney tissues.
  • 序列相似性Belongs to the adrenomedullin family.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Adm antibody
    • ADM precursor antibody
    • ADML_HUMAN antibody
    • AM antibody
    • PAMP antibody
    • Preproadrenomedullin antibody
    • Proadrenomedullin N-20 terminal peptide antibody
    • Proadrenomedullin N20 terminal peptide antibody
    • ProAM N terminal 20 peptide antibody
    • ProAM N-terminal 20 peptide antibody
    • ProAM N20 antibody
    • ProAM-N20 antibody
    • ProAMN20 antibody
    see all

Anti-Adrenomedullin antibody 图像

  • Anti-Adrenomedullin antibody (ab125409) at 1 µg/ml + HepG2 cell lysate at 10 µg

    Predicted band size : 20 kDa

Anti-Adrenomedullin antibody (ab125409)参考文献

ab125409 has not yet been referenced specifically in any publications.

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