概述

  • 产品名称Anti-ADK抗体
    参阅全部 ADK 一抗
  • 描述
    兔多克隆抗体to ADK
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic peptide conjugated to KLH selected within aa 1~100 of human ADK.

  • 阳性对照
    • Mouse bladder tissue lysate.

性能

应用

Our Abpromise guarantee covers the use of ab38010 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/1000.
WB 1/100 - 1/500. Detects a band of approximately 41 kDa (predicted molecular weight: 41 kDa).

靶标

  • 功能ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives. Serves as a potential regulator of concentrations of extracellular adenosine and intracellular adenine nucleotides.
  • 组织特异性Widely expressed. Highest level in placenta, liver, muscle and kidney.
  • 通路Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenosine 3',5'-bisphosphate: step 1/1.
  • 序列相似性Belongs to the carbohydrate kinase pfkB family.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 2310026J05Rik antibody
    • 5033405D03Rik antibody
    • Adenosine 5''-phosphotransferase antibody
    • Adenosine kinase antibody
    • adk antibody
    • ADK_HUMAN antibody
    • AI255373 antibody
    • AI987814 antibody
    • AK antibody
    • MGC6593 antibody
    • OTTHUMP00000019864 antibody
    • OTTHUMP00000019865 antibody
    see all

Anti-ADK antibody 图像

  • Anti-ADK antibody (ab38010) + Mouse bladder tissue lysate.

    Predicted band size : 41 kDa
    Observed band size : 41 kDa
    Additional bands at : ~125 kDa,~150 kDa. We are unsure as to the identity of these extra bands.

Anti-ADK antibody (ab38010)参考文献

This product has been referenced in:
  • Annes JP  et al. Adenosine kinase inhibition selectively promotes rodent and porcine islet ß-cell replication. Proc Natl Acad Sci U S A 109:3915-20 (2012). ICC/IF . Read more (PubMed: 22345561) »

See 1 Publication for this product

Product Wall

Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample Human Tissue sections (Neuroglia)
Antigen retrieval step Heat mediated - Buffer/Enzyme Used: 0.01mol/L citrate buffer solution ( pH6.0)
Permeabilization No
Specification Neuroglia
Blocking step Serum as blocking agent for 30 minute(s) · Concentration: 5% · Temperature: 25°C
Fixative Paraformaldehyde
Username

Dr. xiaoqiang xia

Verified customer

提交于 Apr 13 2016

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Western blot
Sample Mouse Tissue lysate - whole (plasma)
Loading amount 10 µg
Specification plasma
Gel Running Conditions Reduced Denaturing (12% gel)
Blocking step Milk as blocking agent for 1 hour(s) and 30 minute(s) · Concentration: 5% · Temperature: 4°C
Username

Ms. Yoonha Kim

Verified customer

提交于 Sep 11 2009

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"