Anti-Adiponectin Receptor 2抗体(ab77613)

概述

  • 产品名称Anti-Adiponectin Receptor 2抗体
    参阅全部 Adiponectin Receptor 2 一抗
  • 描述
    山羊多克隆抗体to Adiponectin Receptor 2
  • 特异性Recognizes ADPR2 Receptor. Likely to cross react with ADPR1 Receptor.
  • 经测试应用适用于: WB, IHC-P, ICCmore details
  • 种属反应性
    与反应: Mouse, Rat, Human, Macaque Monkey
    预测可用于: Chicken, Cow, Pig
  • 免疫原

    Synthetic peptide:

    YITGAALYAARIPERFFPGKC

    , corresponding to C terminal amino acids 321-341 of human Adiponectin Receptor 2

  • 阳性对照
    • Human liver tissue and human muscle tissue
  • 常规说明


    This antibody may be used in developing sandwitch ELISA assays in combination with antibodies specific to N terminus of ADPR2 Receptor.

相关产品

应用

Our Abpromise guarantee covers the use of ab77613 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000. Predicted molecular weight: 44 kDa.
IHC-P 1/250.

Buffer used: 10 mM KHPO4, 140 mM NaCl, pH 7.2.

ICC 1/400.

Acetone fixed cells.

靶标

  • 功能Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some intermediate-affinity receptor activity for both globular and full-length adiponectin.
  • 组织特异性Highly expressed in skeletal muscle, liver and placenta. Weakly expressed in brain, heart, colon, spleen, kidney, thymus, small intestine, peripheral blood leukocytes and lung.
  • 序列相似性Belongs to the ADIPOR family.
  • 结构域The N-terminus is known to be cytoplasmic while the C-terminus is known to be extracellular.
  • 细胞定位Membrane. Localized to the cell membrane and intracellular organelles.
  • Information by UniProt
  • 数据库链接
  • 别名
    • PAQR2 antibody
    • ACDCR2 antibody
    • Adiponectin receptor protein 2 antibody
    • Adipor2 antibody
    • ADR2_HUMAN antibody
    • Progestin and adipoQ receptor family member II antibody
    see all

Anti-Adiponectin Receptor 2 antibody 图像

  • Paraffin section of human liver tissue stained with antibody to human ADPR2 receptor C-terminus ab77613 at 1/250 dilution.
  • Paraffin section of human muscle tissue stained with antibody to human ADPR2 receptor C-terminus ab77613 at 1/250 dilution.

Anti-Adiponectin Receptor 2 antibody (ab77613)参考文献

ab77613 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your phone call.
DISCOUNT CODE: xxx
Expiration date: xxx
I am very pleased to hear you would like to accept our offer and test ab77613 in drosophila and IHC wholemount. This code will give you 1 free PRIMARY ANTIBODY before...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"