Anti-Adiponectin Receptor 2抗体(ab113538)

概述

  • 产品名称
    Anti-Adiponectin Receptor 2抗体
    参阅全部 Adiponectin Receptor 2 一抗
  • 描述
    兔多克隆抗体to Adiponectin Receptor 2
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Macaque monkey, Gorilla
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 1 - 100 of Human Adiponectin Receptor 2.

  • 阳性对照
    • This antibody gave a positive signal in Human Liver tissue lysate.

性能

应用

Our Abpromise guarantee covers the use of ab113538 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Detects a band of approximately 43 kDa (predicted molecular weight: 43 kDa).

靶标

  • 功能
    Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some intermediate-affinity receptor activity for both globular and full-length adiponectin.
  • 组织特异性
    Highly expressed in skeletal muscle, liver and placenta. Weakly expressed in brain, heart, colon, spleen, kidney, thymus, small intestine, peripheral blood leukocytes and lung.
  • 序列相似性
    Belongs to the ADIPOR family.
  • 结构域
    The N-terminus is known to be cytoplasmic while the C-terminus is known to be extracellular.
  • 细胞定位
    Membrane. Localized to the cell membrane and intracellular organelles.
  • Information by UniProt
  • 数据库链接
  • 别名
    • PAQR2 antibody
    • ACDCR2 antibody
    • Adiponectin receptor protein 2 antibody
    • Adipor2 antibody
    • ADR2_HUMAN antibody
    • Progestin and adipoQ receptor family member II antibody
    see all

图片

  • Anti-Adiponectin Receptor 2 antibody (ab113538) at 1 µg/ml + Human liver tissue lysate - total protein (ab29889) at 10 µg

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 43 kDa
    Observed band size : 43 kDa
    Additional bands at : 60 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 1 minute

实验方案

文献

ab113538 has not yet been referenced specifically in any publications.

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