Anti-Adiponectin Receptor 1抗体[mAbcam50675] (ab50675)

概述

  • 产品名称
    Anti-Adiponectin Receptor 1抗体[mAbcam50675]
    参阅全部 Adiponectin Receptor 1 一抗
  • 描述
    小鼠单克隆抗体[mAbcam50675] to Adiponectin Receptor 1
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Chicken, Zebrafish
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 350 to the C-terminus of Human Adiponectin Receptor 1.

    (Peptide available as ab59184.)

  • 阳性对照
    • This antibody gave a positive signal in Human Skeletal Muscle Lysate.
  • 常规说明

    This antibody clone is manufactured by Abcam.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液
    Preservative: 0.02% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • 纯度
    Concentrated Culture Supernatant
  • 纯化说明
    Tissue culture supernatant was concentrated and then buffer exchanged.
  • 克隆
    单克隆
  • 克隆编号
    mAbcam50675
  • 骨髓瘤
    Sp2/0-Ag14
  • 同种型
    IgM
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab50675 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 10 µg/ml. Detects a band of approximately 42 kDa (predicted molecular weight: 42 kDa).

靶标

  • 功能
    Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some high-affinity receptor for globular adiponectin but low-affinity receptor for full-length adiponectin.
  • 组织特异性
    Widely expressed. Highly expressed in skeletal muscle. Expressed at intermediate level in brain, heart, spleen, kidney, liver, placenta, lung and peripheral blood leukocytes. Weakly expressed in colon, thymus and small intestine.
  • 序列相似性
    Belongs to the ADIPOR family.
  • 结构域
    The N-terminus is known to be cytoplasmic while the C-terminus is known to be extracellular.
  • 细胞定位
    Membrane. Localized to the cell membrane and intracellular organelles.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ACDCR1 antibody
    • ADIPO R1 antibody
    • Adiponectin receptor protein 1 antibody
    • ADIPOR 1 antibody
    • Adipor1 antibody
    • ADR1_HUMAN antibody
    • CGI 45 antibody
    • CGI 45 protein antibody
    • CGI-45 antibody
    • CGI45 antibody
    • CGI45 protein antibody
    • FLJ25385 antibody
    • FLJ42464 antibody
    • PAQR1 antibody
    • Progestin and adipoQ receptor family member I antibody
    • TESBP1A antibody
    see all

Anti-Adiponectin Receptor 1 antibody [mAbcam50675] 图像

  • Anti-Adiponectin Receptor 1 antibody [mAbcam50675] (ab50675) at 10 µg/ml + Human skeletal muscle tissue lysate - total protein (ab29330) at 20 µg

    Secondary
    Goat polyclonal to Mouse IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

    Performed under reducing conditions.

    Predicted band size : 42 kDa
    Observed band size : 42 kDa
    Additional bands at : 28 kDa. We are unsure as to the identity of these extra bands.

实验方案

Anti-Adiponectin Receptor 1 antibody [mAbcam50675] (ab50675)参考文献

This product has been referenced in:
  • Diot M  et al. Expression of adiponectin, chemerin and visfatin in plasma and different tissues during a laying season in turkeys. Reprod Biol Endocrinol 13:81 (2015). WB ; Turkey . Read more (PubMed: 26228641) »

See 1 Publication for this product

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