Anti-Adiponectin Receptor 1抗体(ab125459)

概述

  • 产品名称Anti-Adiponectin Receptor 1抗体
    参阅全部 Adiponectin Receptor 1 一抗
  • 描述
    兔多克隆抗体to Adiponectin Receptor 1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Goat, Horse, Guinea pig, Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within the N terminal amino acids 37-86 (KGKRVIANPP KAEEEQTCPV PQEEEEEVRV LTLPLQAHHA MEKMEEFVYK) of the Human Adiponectin Receptor 1 protein (NP_057083).

性能

应用

Our Abpromise guarantee covers the use of ab125459 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution. Predicted molecular weight: 43 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some high-affinity receptor for globular adiponectin but low-affinity receptor for full-length adiponectin.
  • 组织特异性Widely expressed. Highly expressed in skeletal muscle. Expressed at intermediate level in brain, heart, spleen, kidney, liver, placenta, lung and peripheral blood leukocytes. Weakly expressed in colon, thymus and small intestine.
  • 序列相似性Belongs to the ADIPOR family.
  • 结构域The N-terminus is known to be cytoplasmic while the C-terminus is known to be extracellular.
  • 细胞定位Membrane. Localized to the cell membrane and intracellular organelles.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ACDCR1 antibody
    • ADIPO R1 antibody
    • Adiponectin receptor protein 1 antibody
    • ADIPOR 1 antibody
    • Adipor1 antibody
    • ADR1_HUMAN antibody
    • CGI 45 antibody
    • CGI 45 protein antibody
    • CGI-45 antibody
    • CGI45 antibody
    • CGI45 protein antibody
    • FLJ25385 antibody
    • FLJ42464 antibody
    • PAQR1 antibody
    • Progestin and adipoQ receptor family member I antibody
    • TESBP1A antibody
    see all

Anti-Adiponectin Receptor 1 antibody 图像

  • Anti-Adiponectin Receptor 1 antibody (ab125459) at 1 µg/ml (Anti-ADIPOR1 Antibody) + 293T cell lysates

    Predicted band size : 43 kDa

Anti-Adiponectin Receptor 1 antibody (ab125459)参考文献

ab125459 has not yet been referenced specifically in any publications.

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