Anti-Adiponectin Receptor 1抗体(ab101094)

概述

• 产品名称
  Anti-Adiponectin Receptor 1抗体
  参阅全部 Adiponectin Receptor 1 一抗
• 描述
  兔多克隆抗体to Adiponectin Receptor 1
• 经测试应用
  适用于: WBmore details
• 种属反应性
  与反应: Mouse
  预测可用于: Rat, Human
• 免疫原

  Synthetic peptide surrounding amino acid 23 of mouse AdipoR1

• 阳性对照
  • 3T3 cell lysate

性能

• 形式
  Liquid
• 存放说明
  Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• 存储溶液
  Preservative: 0.01% Thimerosal (merthiolate)
  Constituents: 30% Glycerol, 0.5% BSA, PBS
• Concentration information loading...
• 纯度
  Immunogen affinity purified
• 克隆
  多克隆
• 同种型
  IgG
• 研究领域
  • Cardiovascular
  • Lipids / Lipoproteins
  • Adipose Related
  • Acrp

  • Signal Transduction
  • Growth Factors/Hormones
  • Hormones

相关产品

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

应用

靶标

• 功能
  Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some high-affinity receptor for globular adiponectin but low-affinity receptor for full-length adiponectin.
• 组织特异性
  Widely expressed. Highly expressed in skeletal muscle. Expressed at intermediate level in brain, heart, spleen, kidney, liver, placenta, lung and peripheral blood leukocytes. Weakly expressed in colon, thymus and small intestine.
• 序列相似性
  Belongs to the ADIPOR family.
• 结构域
  The N-terminus is known to be cytoplasmic while the C-terminus is known to be extracellular.
• 细胞定位
  Membrane. Localized to the cell membrane and intracellular organelles.

• Target information above from: UniProt accession Q96A54 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 数据库链接
  • Entrez Gene: 51094 Human
  • Entrez Gene: 72674 Mouse
  • Entrez Gene: 289036 Rat
  • Omim: 607945 Human
  • SwissProt: Q96A54 Human
  • SwissProt: Q91VH1 Mouse
  • Unigene: 5298 Human
  • Unigene: 259976 Mouse

  • Unigene: 104556 Rat

  see all
• 别名
  • ACDCR1 antibody
  • ADIPO R1 antibody
  • Adiponectin receptor protein 1 antibody

  • ADIPOR 1 antibody
  • Adipor1 antibody
  • ADR1_HUMAN antibody
  • CGI 45 antibody
  • CGI 45 protein antibody
  • CGI-45 antibody
  • CGI45 antibody
  • CGI45 protein antibody
  • FLJ25385 antibody
  • FLJ42464 antibody
  • PAQR1 antibody
  • Progestin and adipoQ receptor family member I antibody
  • TESBP1A antibody

  see all

实验方案

• Western blot protocols