概述

  • 产品名称Anti-Adenovirus E1A抗体[M73]
    参阅全部 Adenovirus E1A 一抗
  • 描述
    小鼠单克隆抗体[M73] to Adenovirus E1A
  • 特异性This antibody reacts with Adenovirus-infected cells and tissue. Using Immunoprecipitation it also recognizes adenovirus 2 and 5 E1A proteins, 3 bands at 30-50kDa, as well as, E1A associated proteins.
  • 经测试应用适用于: IP, ICC/IFmore details
  • 种属反应性
    This antibody reacts with adenovirus infected cells and tissues.
  • 免疫原

    Recombinant full length adenovirus 2 E1A protein.

  • 阳性对照
    • 293 cells

性能

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应用

Our Abpromise guarantee covers the use of ab28305 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IP Use a concentration of 1 - 2 µg/ml.
ICC/IF Use at an assay dependent concentration.

靶标

  • 相关性The early region (E1) of the adenovirus genome, responsible for transforming activity, is localized within the left most 11% of the viral genome and consists of two transcriptional units E1A and E1B. E1A is sufficient for partial transformation and immortalization of primary cells. E1A gene products are necessary for normal levels of transcription of the other early regions of the adenovirus genome during productive infection and are able to either activate or repress the transcription of specific cellular genes. E1A forms specific complexes with cellular proteins including p105 causing inhibition of the cell cycle inducing arresting function of p105.
  • 细胞定位Nuclear
  • 别名
    • Control protein E1A antibody
    • E1A antibody

Anti-Adenovirus E1A antibody [M73] (ab28305)参考文献

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