Anti-Adducin (phospho T445)抗体(ab58485)

概述

  • 产品名称Anti-Adducin (phospho T445)抗体
    参阅全部 Adducin 一抗
  • 描述
    兔多克隆抗体to Adducin (phospho T445)
  • 特异性ab58485 detects endogenous levels of Adducin only when phosphorylated at threonine 445.
  • 经测试应用适用于: IHC-P, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic phosphopeptide derived from human ADD1 around the phosphorylation site of threonine 445 (E-K-TP-R-W).

  • 阳性对照
    • Human breast carcinoma tissue

性能

应用

Our Abpromise guarantee covers the use of ab58485 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use at an assay dependent concentration.
ELISA 1/5000.

靶标

  • 相关性Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha and beta adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha and gamma adducins are ubiquitously expressed. In contrast, beta adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca2+/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.
  • 细胞定位Cytoplasm › cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
  • 数据库链接
  • 别名
    • ADD1 antibody
    • ADD2 antibody
    • ADD3 antibody
    • ADDA antibody
    • ADDB antibody
    • ADDL antibody
    • Adducin 1 (alpha) antibody
    • Adducin 1 antibody
    • Adducin 2 (beta) antibody
    • Adducin 2 antibody
    • Adducin 3 (gamma) antibody
    • Adducin 3 antibody
    • Adducin like antibody
    • Alpha adducin antibody
    • Beta adducin antibody
    see all

Anti-Adducin (phospho T445) antibody 图像

  • Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using ab58485 at a dilution of 1/50. Right hand image: treated with immunising peptide. Left hand image: untreated.

Anti-Adducin (phospho T445) antibody (ab58485)参考文献

ab58485 has not yet been referenced specifically in any publications.

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