Anti-ADCY8/AC8抗体(ab196686)
Key features and details
- Rabbit polyclonal to ADCY8/AC8
- Suitable for: IHC-P, ICC/IF
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-ADCY8/AC8抗体 -
描述
兔多克隆抗体to ADCY8/AC8 -
宿主
Rabbit -
经测试应用
适用于: IHC-P, ICC/IFmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat -
免疫原
Synthetic peptide corresponding to Human ADCY8/AC8 (internal sequence).
Database link: P40145 -
阳性对照
- Human brain tissue, A549 cells.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, 49% PBS
PBS is without Mg2+ and Ca2+ -
Concentration information loading...
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纯度
Immunogen affinity purified -
纯化说明
Purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab196686于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
IHC-P | (1) |
1/50 - 1/1000.
|
ICC/IF |
1/100 - 1/500.
|
说明 |
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IHC-P
1/50 - 1/1000. |
ICC/IF
1/100 - 1/500. |
靶标
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相关性
This is a membrane-bound, calcium-inhibitable adenylyl cyclase. It may be involved in learning, in memory and in drug dependence. -
细胞定位
Cell Membrane; multi-pass membrane protein -
数据库链接
- Entrez Gene: 114 Human
- Entrez Gene: 11514 Mouse
- Entrez Gene: 29241 Rat
- Omim: 103070 Human
- SwissProt: P40145 Human
- SwissProt: P97490 Mouse
- SwissProt: P40146 Rat
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别名
- ADCY3 antibody
- Adenylate cyclase 8 antibody
- Adenylate cyclase type VIII antibody
see all
图片
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Immunofluorescence analysis of A549 cells labeling ADCY8/AC8 antibody with ab196686 at 1/100 dilution. Right panel was preincubated with blocking peptide.
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Immunohistochemical analysis of paraffin-embedded Human brain tissue labeling ADCY8/AC8 using ab196686 at 1/50 dilution. Right panel was preincubated with blocking peptide.
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab196686 被引用在 2 文献中.
- Zhang X et al. Endogenous glutamate determines ferroptosis sensitivity via ADCY10-dependent YAP suppression in lung adenocarcinoma. Theranostics 11:5650-5674 (2021). PubMed: 33897873
- Tenner B et al. Spatially compartmentalized phase regulation of a Ca2+-cAMP-PKA oscillatory circuit. Elife 9:N/A (2020). PubMed: 33201801