Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog
Synthetic peptide corresponding to a region within N terminal amino acids 144-193 (FYQGFIRNDS SSSVAVSTCA GLSGLIRTRK NEFLISPLPQ LLAQEHNYSS) of human ADAMTS18 (NP_955387).
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Constituents: 2% Sucrose, PBS
Concentration information loading...
Immunogen affinity purified
affinity chromatography method
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 µg/ml. Predicted molecular weight: 135 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
Expressed in fetal lung, liver, and kidney and in adult brain, prostate, submaxillary gland, and endothelium.
Contains 1 disintegrin domain.
Contains 1 peptidase M12B domain. Contains 1 PLAC domain. Contains 5 TSP type-1 domains.
The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
The precursor is cleaved by a furin endopeptidase.
Secreted > extracellular space > extracellular matrix.
Information by UniProt
A disintegrin and metalloproteinase with thrombospondin motifs 18 antibody
A disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 18 antibody
A disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 21 antibody
Anti-ADAMTS18 antibody 图像
Anti-ADAMTS18 antibody (ab82672)参考文献
has not yet been referenced specifically in any publications.
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