概述

  • 产品名称Anti-ADAMDEC1抗体
    参阅全部 ADAMDEC1 一抗
  • 描述
    小鼠单克隆抗体to ADAMDEC1
  • 经测试应用适用于: IHC-P, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 361-471 of Human ADAMDEC1

性能

应用

Our Abpromise guarantee covers the use of ab57224 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.
    IHC-P: Use at a concentration of 3 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能May play an important role in the control of the immune response and during pregnancy.
    • 组织特异性Expressed highly in the small intestine and appendix, moderately in lymph node, mucosal lining of the colon, thymus, spleen and very weakly in the bone marrow. Predominantly expressed in dendritic cells (DC) of the germinal center. Weakly expressed in monocyte and highly expressed in macrophage. Absent in immature DC.
    • 序列相似性Contains 1 disintegrin domain.
      Contains 1 peptidase M12B domain.
    • 细胞定位Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • A disintegrin and metalloproteinase domain like protein decysin 1 antibody
      • A disintegrin and metalloproteinase domain-like protein decysin-1 antibody
      • ADAM DEC1 antibody
      • ADAM like decysin 1 antibody
      • ADAM like protein decysin 1 antibody
      • ADAM-like protein decysin-1 antibody
      • ADAMDEC 1 antibody
      • Adamdec1 antibody
      • ADEC1_HUMAN antibody
      • Decysin antibody
      • Disintegrin protease antibody
      • M12.219 antibody
      see all

    Anti-ADAMDEC1 antibody 图像

    • ADAMDEC1 antibody (ab57224) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human tonsil.
    • Western blot against tagged recombinant protein immunogen using ab57224 ADAMDEC1 antibody at 1ug/ml. Predicted band size of immunogen is 38 kDa

    Anti-ADAMDEC1 antibody (ab57224)参考文献

    This product has been referenced in:
    • Lund J  et al. Evidence for restricted reactivity of ADAMDEC1 with protein substrates and endogenous inhibitors. J Biol Chem 290:6620-9 (2015). WB . Read more (PubMed: 25564618) »
    • Lund J  et al. ADAMDEC1 is a metzincin metalloprotease with dampened proteolytic activity. J Biol Chem 288:21367-75 (2013). WB . Read more (PubMed: 23754285) »

    See all 2 Publications for this product

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