Anti-ADAM9抗体(ab186833)
Key features and details
- Rabbit polyclonal to ADAM9
- Suitable for: ICC/IF, WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术,可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-ADAM9抗体
参阅全部 ADAM9 一抗 -
描述
兔多克隆抗体to ADAM9 -
宿主
Rabbit -
经测试应用
适用于: ICC/IF, WB, IHC-Pmore details -
种属反应性
与反应: Mouse, Human -
免疫原
Recombinant fragment corresponding to Human ADAM9 aa 475-685 (internal sequence).
Database link: Q13443 -
阳性对照
- Mouse kidney and liver extracts.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Related Products
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab186833于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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ICC/IF |
Use at an assay dependent concentration.
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WB |
1/500 - 1/2000. Predicted molecular weight: 91 kDa.
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IHC-P |
1/50 - 1/200.
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说明 |
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ICC/IF
Use at an assay dependent concentration. |
WB
1/500 - 1/2000. Predicted molecular weight: 91 kDa. |
IHC-P
1/50 - 1/200. |
靶标
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相关性
ADAM9 encodes disintegrin and metalloprotease (ADAM) domain 9, which is a member of the ADAM protein family. Members of this family are membrane- anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell- cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The member encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. -
细胞定位
Isoform 1: Cell membrane; single-pass type I membrane protein. Isoform 2: Secreted protein. -
数据库链接
- Entrez Gene: 8754 Human
- Entrez Gene: 11502 Mouse
- Omim: 602713 Human
- SwissProt: Q13443 Human
- SwissProt: Q61072 Mouse
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别名
- A disintegrin and metalloproteinase domain 9 antibody
- ADAM 9 antibody
- ADAM metallopeptidase domain 9 antibody
see all
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human liver cancer tissue labelling ADAM9 with ab186833 at 1/200. Magnification: 400x.
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Immunocytochemistry/Immunofluorescence analysis of U2OS cells using ab186833. Blue DAPI for nuclear staining.
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All lanes : Anti-ADAM9 antibody (ab186833) at 1/500 dilution
Lane 1 : Mouse kidney extract
Lane 2 : Mouse liver extract
Predicted band size: 91 kDa
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (15)
ab186833 被引用在 15 文献中.
- Xiao Y et al. Ubiquitin-specific peptidase 39 promotes human glioma cells migration and invasion by facilitating ADAM9 mRNA maturation. Mol Oncol 16:388-404 (2022). PubMed: 33811456
- Li D et al. IL-17A Promotes Epithelial ADAM9 Expression in Cigarette Smoke-Related COPD. Int J Chron Obstruct Pulmon Dis 17:2589-2602 (2022). PubMed: 36267325
- Goel K et al. Characterization of pulmonary vascular remodeling and MicroRNA-126-targets in COPD-pulmonary hypertension. Respir Res 23:349 (2022). PubMed: 36522710
- Kim DY et al. Involvement of Klotho, TNF-α and ADAMs in radiation-induced senescence of renal epithelial cells. Mol Med Rep 23:N/A (2021). PubMed: 33179086
- Liu B et al. mir-126-5p Promotes Cisplatin Sensitivity of Non-Small-Cell Lung Cancer by Inhibiting ADAM9. Biomed Res Int 2021:6622342 (2021). PubMed: 34055989