概述

  • 产品名称Anti-ADAM20抗体
    参阅全部 ADAM20 一抗
  • 描述
    兔多克隆抗体to ADAM20
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide against internal sequence amino acid of Human ADAM20 (NP_003805.3) conjugated to KLH.

  • 阳性对照
    • Human Prostate, Human Testis

性能

应用

Our Abpromise guarantee covers the use of ab118612 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use a concentration of 15 - 20 µg/ml.

靶标

  • 功能May be involved in sperm maturation and/or fertilization.
  • 组织特异性Testis specific.
  • 序列相似性Contains 1 disintegrin domain.
    Contains 1 EGF-like domain.
    Contains 1 peptidase M12B domain.
  • 结构域A tripeptide motif (VGE) within disintegrin-like domain could be involved in the binding to egg integrin receptor and thus could mediate sperm/egg binding.
    The cysteine-rich domain encodes putative cell-fusion peptides, which could be involved in sperm-egg fusion.
    The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
  • 翻译后修饰Has no obvious cleavage site for furin endopeptidase, suggesting that the proteolytic processing is regulated.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • A disintegrin and metalloproteinase domain 20 antibody
    • A disintegrin and metalloproteinase domain 20 preproprotein antibody
    • ADA20_HUMAN antibody
    • ADAM 20 antibody
    • ADAM metallopeptidase domain 20 antibody
    • ADAM20 antibody
    • Disintegrin and metalloproteinase domain-containing protein 20 antibody
    • OTTHUMP00000236151 antibody
    see all

Anti-ADAM20 antibody 图像

  • ab118612 at 15 µg/ml staining ADAM20 in Formalin-fixed, Paraffin-embedded Human Prostate tissue by Immunohistochemistry.
  • ab118612 at 15 µg/ml staining ADAM20 in Formalin-fixed, Paraffin-embedded Human Testis tissue by Immunohistochemistry.

Anti-ADAM20 antibody (ab118612)参考文献

ab118612 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab118612.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"