概述

  • 产品名称Anti-ADAM2抗体
    参阅全部 ADAM2 一抗
  • 描述
    小鼠单克隆抗体to ADAM2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Recombinant Fragment
    预测可用于: Human
  • 免疫原

    Recombinant fragment: RLDPFFKQQA VCGNAKLEAG EECDCGTEQD CALIGETCCD IATCRFKAGS NCAEGPCCEN CLFMSKERMC RPSFEECDLP EYCNGSSASC PENHYVQTGH , corresponding to amino acids 376-476 of Human ADAM2

性能

应用

Our Abpromise guarantee covers the use of ab55028 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein.
    • 组织特异性Expressed specifically in spermatogenic cells in the seminiferous cells. Not detected in fetal tissues.
    • 序列相似性Contains 1 disintegrin domain.
      Contains 1 EGF-like domain.
      Contains 1 peptidase M12B domain.
    • 结构域A tripeptide motif (FEE) within disintegrin-like domain could be involved in the binding to egg integrin receptor and thus could mediate sperm/egg binding.
    • 翻译后修饰The prodomain and the metalloprotease domain are cleaved during the epididymal maturation of the spermatozoa.
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • A disintegrin and metalloproteinase domain 2 antibody
      • ADAM 2 antibody
      • ADAM metallopeptidase domain 2 antibody
      • Adam2 antibody
      • ADAM2_HUMAN antibody
      • AI323749 antibody
      • Cancer/testis antigen 15 antibody
      • CRYN1 antibody
      • CRYN2 antibody
      • CT15 antibody
      • Disintegrin and metalloproteinase domain-containing protein 2 antibody
      • Fertilin beta antibody
      • Fertilin subunit beta antibody
      • Ftnb antibody
      • PH 30 antibody
      • PH 30b antibody
      • PH-30 antibody
      • PH30 antibody
      • Ph30 beta antibody
      • PH30-beta antibody
      see all

    Anti-ADAM2 antibody 图像

    • Western blot against tagged recombinant protein immunogen using ab55028 ADAM2 antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa.

      This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Anti-ADAM2 antibody (ab55028)参考文献

    ab55028 has not yet been referenced specifically in any publications.

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