Anti-Acylglycerol Kinase抗体(ab77266)

概述

• 产品名称Anti-Acylglycerol Kinase抗体
  参阅全部 Acylglycerol Kinase 一抗
• 描述
  山羊多克隆抗体to Acylglycerol Kinase
• 经测试应用适用于: WB, ELISAmore details
• 种属反应性
  与反应: Human
  预测可用于: Mouse
• 免疫原

  Synthetic peptide:

  CDPRKREQMLTSP

  , corresponding to C terminal amino acids 408-420 of Human Acylglycerol Kinase (NP_060708.1).
  Run BLAST with Run BLAST with
• 阳性对照
  • Lysate from Human Brain (Substantia nigra, Hippocampus)

性能

• 形式Liquid
• 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• 存储溶液Preservative: 0.02% Sodium Azide
  Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
• Concentration information loading...
• 纯度Immunogen affinity purified
• 纯化说明Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• 克隆多克隆
• 同种型IgG
• 研究领域
  • Signal Transduction
  • Signaling Pathway
  • Lipid Signaling
  • Lipid Kinases

  • Signal Transduction
  • Signaling Pathway
  • Lipid Signaling
  • Other

  • Signal Transduction
  • Metabolism
  • Lipid metabolism

  • Cancer
  • Tumor biomarkers
  • Enzymes
  • Other

  • Metabolism
  • Types of disease
  • Cancer

相关产品

• Compatible Secondaries
  • Donkey Anti-Goat IgG H&L (Alexa Fluor® 488) (ab150129)
  • Donkey Anti-Goat IgG H&L (HRP) (ab205723)

应用

靶标

• 功能Lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. Does not phosphorylate sphingosine. Overexpression increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth.
• 组织特异性Highly expressed in muscle, heart, kidney and brain.
• 通路Lipid metabolism; glycerolipid metabolism.
• 序列相似性Contains 1 DAGKc domain.
• 细胞定位Mitochondrion membrane.

• Target information above from: UniProt accession Q53H12 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 数据库链接
  • Entrez Gene: 55750 Human
  • Entrez Gene: 69923 Mouse
  • Omim: 610345 Human
  • SwissProt: Q53H12 Human
  • SwissProt: Q9ESW4 Mouse
  • Unigene: 699361 Human
  • Unigene: 32840 Mouse
• 别名
  • 2610037M15Rik antibody
  • 6720408I04Rik antibody
  • Acylglycerol kinase mitochondrial antibody

  • Acylglycerol kinase, mitochondrial antibody
  • agk antibody
  • AGK_HUMAN antibody
  • AI465370 antibody
  • FLJ10842 antibody
  • hAGK antibody
  • HsMuLK antibody
  • MuLK antibody
  • Multi substrate lipid kinase antibody
  • Multi-substrate lipid kinase antibody
  • Multiple substrate lipid kinase antibody
  • RGD1562046 antibody

  see all