Anti-Acylglycerol Kinase抗体(ab77266)

概述

  • 产品名称Anti-Acylglycerol Kinase抗体
    参阅全部 Acylglycerol Kinase 一抗
  • 描述
    山羊多克隆抗体to Acylglycerol Kinase
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide:

    CDPRKREQMLTSP

    , corresponding to C terminal amino acids 408-420 of Human Acylglycerol Kinase (NP_060708.1).

  • 阳性对照
    • Lysate from Human Brain (Substantia nigra, Hippocampus)

性能

应用

Our Abpromise guarantee covers the use of ab77266 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明Peptide ELISA: Use at an assay dependent dilution. Antibody detection limit dilution: 1/16000.
    WB: Use at a concentration of 1 - 3 µg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 47 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. Does not phosphorylate sphingosine. Overexpression increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth.
    • 组织特异性Highly expressed in muscle, heart, kidney and brain.
    • 通路Lipid metabolism; glycerolipid metabolism.
    • 序列相似性Contains 1 DAGKc domain.
    • 细胞定位Mitochondrion membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 2610037M15Rik antibody
      • 6720408I04Rik antibody
      • Acylglycerol kinase mitochondrial antibody
      • Acylglycerol kinase, mitochondrial antibody
      • agk antibody
      • AGK_HUMAN antibody
      • AI465370 antibody
      • FLJ10842 antibody
      • hAGK antibody
      • HsMuLK antibody
      • MuLK antibody
      • Multi substrate lipid kinase antibody
      • Multi-substrate lipid kinase antibody
      • Multiple substrate lipid kinase antibody
      • RGD1562046 antibody
      see all

    Anti-Acylglycerol Kinase antibody 图像

    • Anti-Acylglycerol Kinase antibody (ab77266) at 1 µg/ml + Human Brain (Substantia nigra) lysate in RIPA buffer at 35 µg

      Predicted band size : 47 kDa
      Observed band size : 47 kDa
      Additional bands at : 22 kDa. We are unsure as to the identity of these extra bands.

    Anti-Acylglycerol Kinase antibody (ab77266)参考文献

    ab77266 has not yet been referenced specifically in any publications.

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