Anti-Activin A Receptor Type IC抗体(ab77051)


  • 产品名称Anti-Activin A Receptor Type IC抗体
    参阅全部 Activin A Receptor Type IC 一抗
  • 描述
    兔多克隆抗体to Activin A Receptor Type IC
  • 特异性ab77051 is predicted to have no cross-reactivity to ACVR1 or ACVR1B.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic 15 amino acid peptide from near the N terminus of Human Activin A Receptor Type IC (NP_001096).

  • 阳性对照
    • Human placenta tissue lysate.



Our Abpromise guarantee covers the use of ab77051 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 55 kDa.Can be blocked with Activin A Receptor Type IC peptide (ab166744).


  • 功能Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
  • 组织特异性Present in pancreas, heart, colon, small intestine, ovary and the hippocampus, medulla oblongata and putamen of the brain. Isoform 1, isoform 2, isoform 3 and isoform 4 are all expressed in the placenta throughout pregnancy.
  • 序列相似性Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    Contains 1 GS domain.
    Contains 1 protein kinase domain.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Activin A receptor, type IC antibody
    • Activin receptor like kinase 7 antibody
    • Activin receptor type 1C precursor antibody
    • Activin receptor type IC antibody
    • Activin receptor type-1C antibody
    • Activin receptor-like kinase 7 antibody
    • ACTR IC antibody
    • ACTR-IC antibody
    • ACTRIC antibody
    • ACV1C_HUMAN antibody
    • Acvr1c antibody
    • ACVRLK7 antibody
    • ALK 7 antibody
    • ALK-7 antibody
    • ALK7 antibody
    see all

Anti-Activin A Receptor Type IC antibody 图像

  • Lane 1 : Anti-Activin A Receptor Type IC antibody (ab77051) at 1 µg/ml
    Lane 2 : Anti-Activin A Receptor Type IC antibody (ab77051) at 2 µg/ml

    Lane 1 : Human placenta lysate
    Lane 2 : Human placenta lysate

    Lysates/proteins at 15 µg per lane.

    Predicted band size : 55 kDa
    Observed band size : 60 kDa (why is the actual band size different from the predicted?)

Anti-Activin A Receptor Type IC antibody (ab77051)参考文献

ab77051 has not yet been referenced specifically in any publications.

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