Anti-Activin A Receptor Type IB抗体[MM0054-11A7] (ab78415)

概述

  • 产品名称Anti-Activin A Receptor Type IB抗体[MM0054-11A7]
    参阅全部 Activin A Receptor Type IB 一抗
  • 描述
    小鼠单克隆抗体[MM0054-11A7] to Activin A Receptor Type IB
  • 特异性ab78415 detects Activin A Receptor Type IB (ALK4). No cross reactivity was found to Activin A Receptor Type IA (ALK2).
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant human Activin A Receptor Type IB extracellular domain

  • 常规说明


    This antibody was produced from a hybridoma (mouse myeloma) fused with spleen cells from an immunized mouse.

性能

应用

Our Abpromise guarantee covers the use of ab78415 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/1000. Predicted molecular weight: 57 kDa.
IHC-P 1/50.

靶标

  • 功能On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Phosphorylates TDP2.
  • 组织特异性Expressed in many tissues, most strongly in kidney, pancreas, brain, lung, and liver.
  • 序列相似性Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    Contains 1 GS domain.
    Contains 1 protein kinase domain.
  • 翻译后修饰Autophosphorylated.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 形式There are 3 isoforms produced by alternative splicing. Isoform 1 also known as SKR2-1; isoform 2 as SKR2-2; isoform 3 as SKR2-3.
  • 别名
    • Activin A receptor type 1B antibody
    • Activin A receptor type II like kinase 4 antibody
    • Activin A type 1B receptor antibody
    • Activin A type IB receptor antibody
    • Activin receptor like kinase 4 antibody
    • Activin receptor type 1B antibody
    • Activin receptor type IB antibody
    • Activin receptor type-1B antibody
    • Activin receptor-like kinase 4 antibody
    • ACTR IB antibody
    • ACTR-IB antibody
    • ACTRIB antibody
    • ACV1B_HUMAN antibody
    • ACVR 1B antibody
    • Acvr1b antibody
    • ACVRLK 4 antibody
    • ACVRLK4 antibody
    • ALK 4 antibody
    • ALK-4 antibody
    • ALK4 antibody
    • Serine(threonine) protein kinase receptor R2 antibody
    • Serine/threonine-protein kinase receptor R2 antibody
    • SKR 2 antibody
    • SKR2 antibody
    see all

Anti-Activin A Receptor Type IB antibody [MM0054-11A7] 图像

  • ab78415 at 1/50 dilution, staining Activin A Receptor Type IB in human placental tissue section by Immunohistochemistry (Formalin/PFA fixed paraffin-embedded sections).

Anti-Activin A Receptor Type IB antibody [MM0054-11A7] (ab78415)参考文献

ab78415 has not yet been referenced specifically in any publications.

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