Active人UCH37全长蛋白质(ab124871)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionQ9Y5K5
    • 种属Human
    • 序列MGSSHHHHHHSSGLVPRGSH MTGNAGEWCL MESDPGVFTE LIKGFGCRGA QVEEIWSLEP ENFEKLKPVH GLIFLFKWQP GEEPAGSVVQ DSRLDTIFFA KQVINNACAT QAIVSVLLNC THQDVHLGET LSEFKEFSQS FDAAMKGLAL SNSDVIRQVH NSFARQQMFE FDTKTSAKEE DAFHFVSYVP VNGRLYELDG LREGPIDLGA CNQDDWISAV RPVIEKRIQK YSEGEIRFNL MAIVSDRKMI YEQKIAELQR QLAEEEPMDT DQGNSMLSAI QSEVAKNQML IEEEVQKLKR YKIENIRRKH NYLPFIMELL KTLAEHQQLI PLVEKAKEKQ NAKKAQETK
    • 分子量40 kDa including tags
    • 氨基酸1 to 329
    • 标签His tag N-Terminus
    • 额外的序列信息UCHL5 produced in E.Coli is a single, non-glycosylated polypeptide chain containing349 amino acids (1-329a.a.) and having a molecular mass of 39.7kDa.

技术指标

Our Abpromise guarantee covers the use of ab124871 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性Specific activity: > 500 pmole/min/ug. Measured by the hydrolysis of Ubiquitin-AMC at pH 8.0, at 37°C.
  • 应用

    SDS-PAGE

    Functional Studies

  • 纯度> 90 % SDS-PAGE.
    ab124871 is purified by proprietary chromatographic techniques and is sterile filtered.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.002% PMSF, 0.08% DTT, 0.32% Tris HCl, 0.06% EDTA, 30% Glycerol, 1.17% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • UCH37
    • AD-019
    • CGI 70
    • INO80 complex subunit R
    • INO80R
    • Ubiquitin C terminal hydrolase UCH37
    • Ubiquitin C-terminal hydrolase UCH37
    • Ubiquitin carboxyl terminal esterase L5
    • Ubiquitin carboxyl terminal hydrolase isozyme L5
    • Ubiquitin carboxyl terminal hydrolase L5
    • Ubiquitin carboxyl-terminal hydrolase isozyme L5
    • Ubiquitin thioesterase L5
    • Ubiquitin thiolesterase L5
    • UCH L5
    • UCH-L5
    • UCHL5
    • UCHL5_HUMAN
    see all
  • 功能Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome.
  • 序列相似性Belongs to the peptidase C12 family.
  • 细胞定位Cytoplasm. Nucleus. Associates with the proteasome 19S subunit in the cytoplasm. Associates with the INO80 complex in the nucleus.
  • Information by UniProt

Active human UCH37 full length protein (ab124871)参考文献

ab124871 has not yet been referenced specifically in any publications.

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