概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human

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技术指标

Our Abpromise guarantee covers the use of ab40023 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性Blocking the activity of TOLLIP antibody.
  • 应用

    Blocking - Blocking peptide for Anti-Tollip antibody (ab37155)

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: 0.02% Sodium Azide
    Constituents: 0.1% BSA, PBS, pH 7.2

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • Adapter protein
    • FLJ33531
    • IL 1RAcPIP
    • IL1RAcPIP
    • TOLIP
    • TOLIP_HUMAN
    • Toll interacting protein
    • Toll-interacting protein
    • tollip
    see all
  • 功能Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity.
  • 序列相似性Belongs to the tollip family.
    Contains 1 C2 domain.
    Contains 1 CUE domain.
  • 翻译后修饰Phosphorylated by IRAK1 upon stimulation by IL-1 or microbial products.
  • 细胞定位Cytoplasm.
  • Information by UniProt

Active human Tollip peptide (ab40023)参考文献

ab40023 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"