Active人Semaphorin 3A肽(ab88818)

概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human
    • 序列Semaphorin 3A synthetic peptide corresponds to amino acids in the central region of human Sema3A. This sequence is highly conserved in rat and mouse Sema3A, and has low homology to other semaphorin family members.

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技术指标

Our Abpromise guarantee covers the use of ab88818 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性The peptide is specifically recognized by anti-Sema3A (Central region) antibody (ab23393) in ELISA, and has been shown to block the reactivity of ab23393 during Western blot. In addition, the peptide is recommended for use in blocking ab23393 reactivity in immunocytochemistry.
  • 应用

    Blocking - Blocking peptide for Anti-Semaphorin 3A antibody (ab23393)

    ELISA

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: 0.05% Sodium Azide
    Constituents: PBS

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • Coll 1
    • Coll1
    • HH16
    • Hsema I
    • Hsema III
    • Sema domain immunoglobulin domain (Ig) short basic domain secreted (semaphorin) 3A
    • Sema III
    • SEMA1
    • SEMA1-PEN
    • SEMA3A
    • SEMAD
    • SEMAIII
    • SEMAL
    • Semaphorin 3A precursor
    • Semaphorin III
    • Semaphorin like growth cone guidance homolog of chick collapsin
    • Semaphorin3A
    • SemD
    see all
  • 相关性One family of inhibitory axon guidance molecules is the semaphorins. The semaphorins include secreted, transmembrane, and GPI anchored extracellular molecules that are involved in regulating axon guidance by inhibiting axons from growing toward incorrect targets. Semaphorin 3A (Sema3A) may play a particularly interesting role in limiting axon regeneration since it is expressed in meningeal fibroblasts that invade the injured spinal cord and surround the glial scar. In addition, the Sema3A co receptors, Neuropilin 1 and Plexin A1, are expressed on axons that regenerate up to the injured region, but do not cross this Sema3A containing region. Thus, Sema3A and its co receptors may have important roles in regulating axon guidance during neuronal development and after neuronal injury.
  • 细胞定位Secreted

Active human Semaphorin 3A peptide (ab88818)参考文献

ab88818 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"