概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human

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技术指标

Our Abpromise guarantee covers the use of ab39861 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性This peptide is used for blocking the activity of the Anti-RHEB antibody (ab25873).
  • 应用

    Blocking

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: 0.02% Sodium Azide
    Constituents: 0.1% BSA, PBS, pH 7.2

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • Ras homolog enriched in brain 2, formerly
    • GTP binding protein Rheb
    • GTP-binding protein Rheb
    • MGC111559
    • Ras homolog enriched in brain
    • Ras homolog enriched in brain 2
    • Rheb
    • RHEB 2
    • RHEB_HUMAN
    • RHEB2
    • RHEB2, formerly
    see all
  • 功能Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Activates the protein kinase activity of mTORC1. Has low intrinsic GTPase activity.
  • 组织特异性Ubiquitous. Highest levels observed in skeletal and cardiac muscle.
  • 序列相似性Belongs to the small GTPase superfamily. Rheb family.
  • 翻译后修饰Farnesylation is important for efficiently activating mTORC1-mediated signaling.
  • 细胞定位Cell membrane.
  • Information by UniProt

Active human RHEB peptide (ab39861)参考文献

ab39861 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"