Anti-Actin Regulatory Protein CAPG抗体(ab14235)

概述

  • 产品名称Anti-Actin Regulatory Protein CAPG抗体
    参阅全部 Actin Regulatory Protein CAPG 一抗
  • 描述
    鸡多克隆抗体to Actin Regulatory Protein CAPG
  • 经测试应用适用于: WB, IHC-Frmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 1-348 of Human Actin Regulatory Protein CAPG

性能

应用

Our Abpromise guarantee covers the use of ab14235 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
IHC-Fr
  • 应用说明IHC-Fr: 1/3000 (See PMID 18709641).
    WB: 1/1000. Predicted molecular weight: 39 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA.
    • 组织特异性Macrophages and macrophage-like cells.
    • 序列相似性Belongs to the villin/gelsolin family.
      Contains 3 gelsolin-like repeats.
    • 翻译后修饰The N-terminus is blocked.
    • 细胞定位Cytoplasm. Nucleus. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Actin capping protein GCAP39 antibody
      • Actin regulatory protein CAP G antibody
      • Actin regulatory protein CAP-G antibody
      • AFCP antibody
      • Capg antibody
      • CAPG_HUMAN antibody
      • Capping protein (actin filament) gelsolin like antibody
      • Capping protein gelsolin like antibody
      • Epididymis secretory protein Li 66 antibody
      • gCap39 antibody
      • Gelsolin like capping protein antibody
      • HEL S 66 antibody
      • Macrophage capping protein antibody
      • Macrophage-capping protein antibody
      • mbh1 antibody
      • MCP antibody
      • Myc basic motif homolog 1 antibody
      see all

    Anti-Actin Regulatory Protein CAPG antibody (ab14235)参考文献

    This product has been referenced in:
    • Partheen K  et al. External validation suggests Integrin beta 3 as prognostic biomarker in serous ovarian adenocarcinomas. BMC Cancer 9:336 (2009). WB ; Human . Read more (PubMed: 19775429) »
    • Partheen K  et al. Four potential biomarkers as prognostic factors in stage III serous ovarian adenocarcinomas. Int J Cancer 123:2130-7 (2008). WB, IHC-Fr ; Human . Read more (PubMed: 18709641) »

    See all 3 Publications for this product

    Product Wall

    Abcam guarantees this product to work in the species/application used in this Abreview.
    Application Western blot
    Sample Human Tissue lysate - whole (ovarian tumor)
    Specification ovarian tumor
    Gel Running Conditions Reduced Denaturing
    Blocking step Milk as blocking agent for 15 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 4°C
    Username

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    Verified customer

    提交于 Oct 08 2007

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"