Anti-Acrolein抗体[5F6] (ab48501)

概述

  • 产品名称Anti-Acrolein抗体[5F6]
    参阅全部 Acrolein 一抗
  • 描述
    小鼠单克隆抗体[5F6] to Acrolein
  • 特异性This antibody is specific for Acrolein modified protein (especially FDP-lysine type derivative).
  • 经测试应用适用于: IHC-Pmore details
  • 免疫原

    Acrolein modified keyhole-lympet hemocyanine

  • 阳性对照
    • Aortic wall in the renal tissue of diabetic nephropathy or aortic wall of atherosclerosis.

性能

应用

Our Abpromise guarantee covers the use of ab48501 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use a concentration of 0.5 - 1 µg/ml. Perform heat mediated antigen retrieval via the microwave method before commencing with IHC staining protocol.

靶标

  • 相关性Acrolein, a reactive alpha,beta-unsaturated aldehyde, is a common environmental pollutant, a metabolite of the anticancer drug cyclophosphamide, and a byproduct of lipid peroxidation. An increase in acrolein production has been proposed as a marker for Alzheimer's disease, diabetic glomerular lesions, and atherosclerosis. Acrolein is a potent inhibitor of cell proliferation at nonlethal doses and may act through effects on redox-regulated transcription factors. It has been reported that NF-kappaB activation is inhibited by acrolein.
  • 别名
    • 2-Propen-1-one antibody
    • 2-propenal antibody
    • Acraldehyde antibody
    • Acrolein antibody
    • Acrylic aldehyde antibody
    see all

Anti-Acrolein antibody [5F6] 图像

  • Immunohiostochemical analysis of Acrolein modified proteins expression in formalin fixed paraffin embedded atherosclerotic aorta using ab48501 at 0.5 µg/ml.

Anti-Acrolein antibody [5F6] (ab48501)参考文献

ab48501 has not yet been referenced specifically in any publications.

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