概述

  • 产品名称
    Anti-ACPL2抗体
  • 描述
    兔多克隆抗体to ACPL2
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 306-335 of Human ACPL2 (Accessions: NP_689495.1, NP_001032249.1, Q8TE99)

  • 阳性对照
    • HL-60 cell line lysates.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • 存储溶液
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 纯化说明
    Purified through a protein A column, followed by peptide affinity purification.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab124190 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 55 kDa.

靶标

  • 功能
    Responsible for the 2-O-dephosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature glycosaminoglycan (GAG) chains. Sulfated glycosaminoglycans (GAGs), including heparan sulfate and chondroitin sulfate, are synthesized on the so-called common GAG-protein linkage region (GlcUAbeta1-3Galbeta1-3Galbeta1-4Xylbeta1-O-Ser) of core proteins, which is formed by the stepwise addition of monosaccharide residues by the respective specific glycosyltransferases. Xylose 2-O-dephosphorylation during completion of linkage region formation is a prerequisite for the initiation and efficient elongation of the repeating disaccharide region of GAG chains.
  • 组织特异性
    Widely expressed. Strongly expressed in spleen, fetal liver, moderately in placenta, pancreas, kidney, thymus and colon.
  • 序列相似性
    Belongs to the histidine acid phosphatase family.
  • 细胞定位
    Golgi apparatus membrane. Colocalizes to Golgi apparatus in a B3GAT3-dependent manner.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 2-phosphoxylose phosphatase 1 antibody
    • acid phosphatase-like 2 antibody
    • Acid phosphatase-like protein 2 antibody
    • EC=3.1.3.2 antibody
    • epididymis luminal protein 124 antibody
    • PXYLP1 antibody
    • PXYP1_HUMAN antibody
    • Xylosyl phosphatase antibody
    see all

Anti-ACPL2 antibody 图像

  • Anti-ACPL2 antibody (ab124190) at 1/100 dilution + HL60 cell line lysates at 35 µg

    Predicted band size : 55 kDa

实验方案

Anti-ACPL2 antibody (ab124190)参考文献

ab124190 has not yet been referenced specifically in any publications.

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