Anti-ACOX1抗体- C-terminal (ab71483)

概述

• 产品名称
  Anti-ACOX1抗体- C-terminal
  参阅全部 ACOX1 一抗
• 描述
  兔多克隆抗体to ACOX1 - C-terminal
• 经测试应用
  适用于: WB, ELISAmore details
• 种属反应性
  与反应: Human
  
• 免疫原

  A KLH conjugated synthetic peptide selected from the C-terminal region of human ACOX1.

性能

• 形式
  Liquid
• 存放说明
  Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• 存储溶液
  Preservative: 0.09% Sodium Azide
  Constituents: PBS
• Concentration information loading...
• 纯度
  Protein G purified
• 克隆
  多克隆
• 同种型
  IgG
• 研究领域
  • Signal Transduction
  • Metabolism
  • Lipid metabolism

  • Cardiovascular
  • Lipids / Lipoproteins
  • Fatty Acids
  • Metabolism

  • Cancer
  • Cancer Metabolism
  • Metabolic signaling pathway
  • Metabolism of lipids and lipoproteins

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Lipid and lipoprotein metabolism
  • Lipid metabolism

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Lipid and lipoprotein metabolism
  • Fatty acids

  • Metabolism
  • Types of disease
  • Cancer

  • Metabolism
  • Pathways and Processes
  • Redox metabolism
  • Fatty acid oxidation

相关产品

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

应用

靶标

• 功能
  Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. Isoform 1 shows highest activity against medium-chain fatty acyl-CoAs and activity decreases with increasing chain length. Isoform 2 is active against a much broader range of substrates and shows activity towards very long-chain acyl-CoAs. Isoform 2 is twice as active as isoform 1 against 16-hydroxy-palmitoyl-CoA and is 25% more active against 1,16-hexadecanodioyl-CoA.
• 组织特异性
  Widely expressed with highest levels of isoform 1 and isoform 2 detected in testis. Isoform 1 is expressed at higher levels than isoform 2 in liver and kidney while isoform 2 levels are higher in brain, lung, muscle, white adipose tissue and testis. Levels are almost equal in heart.
• 通路
  Lipid metabolism; peroxisomal fatty acid beta-oxidation.
• 疾病相关
  Adrenoleukodystrophy, pseudoneonatal
• 序列相似性
  Belongs to the acyl-CoA oxidase family.
• 细胞定位
  Peroxisome.

• Target information above from: UniProt accession Q15067 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 数据库链接
  • Entrez Gene: 51 Human
  • Omim: 609751 Human
  • SwissProt: Q15067 Human
  • Unigene: 464137 Human
• 别名
  • ACOX antibody
  • ACOX1 antibody
  • ACOX1_HUMAN antibody

  • Acyl CoA oxidase 1 palmitoyl antibody
  • Acyl CoA oxidase straight chain antibody
  • AOX antibody
  • EC 1.3.3.6 antibody
  • PALMCOX antibody
  • Palmitoyl CoA oxidase antibody
  • Palmitoyl-CoA oxidase antibody
  • Peroxisomal acyl coenzyme A oxidase 1 antibody
  • Peroxisomal acyl-coenzyme A oxidase 1 antibody
  • Peroxisomal fatty acyl CoA oxidase antibody
  • SCOX antibody
  • Straight chain acyl CoA oxidase antibody
  • Straight-chain acyl-CoA oxidase antibody

  see all

实验方案

• Western blot protocols