Anti-ACOX1抗体- C-terminal (ab71483)

Submit an Abreview Submit a Question

概述

  • 产品名称
    Anti-ACOX1抗体- C-terminal
    参阅全部 ACOX1 一抗
  • 描述
    兔多克隆抗体to ACOX1 - C-terminal
  • 宿主
    Rabbit
  • 经测试应用
    适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    A KLH conjugated synthetic peptide selected from the C-terminal region of human ACOX1.

应用

Our Abpromise guarantee covers the use of ab71483 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/50 - 1/100. Detects a band of approximately 74 kDa (predicted molecular weight: 74 kDa).
ELISA 1/1000.

靶标

  • 功能
    Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. Isoform 1 shows highest activity against medium-chain fatty acyl-CoAs and activity decreases with increasing chain length. Isoform 2 is active against a much broader range of substrates and shows activity towards very long-chain acyl-CoAs. Isoform 2 is twice as active as isoform 1 against 16-hydroxy-palmitoyl-CoA and is 25% more active against 1,16-hexadecanodioyl-CoA.
  • 组织特异性
    Widely expressed with highest levels of isoform 1 and isoform 2 detected in testis. Isoform 1 is expressed at higher levels than isoform 2 in liver and kidney while isoform 2 levels are higher in brain, lung, muscle, white adipose tissue and testis. Levels are almost equal in heart.
  • 通路
    Lipid metabolism; peroxisomal fatty acid beta-oxidation.
  • 疾病相关
    Adrenoleukodystrophy, pseudoneonatal
  • 序列相似性
    Belongs to the acyl-CoA oxidase family.
  • 细胞定位
    Peroxisome.
  • Information by UniProt
  • 数据库链接
    • 别名
      • ACOX antibody
      • ACOX1 antibody
      • ACOX1_HUMAN antibody
      • Acyl CoA oxidase 1 palmitoyl antibody
      • Acyl CoA oxidase straight chain antibody
      • AOX antibody
      • EC 1.3.3.6 antibody
      • PALMCOX antibody
      • Palmitoyl CoA oxidase antibody
      • Palmitoyl-CoA oxidase antibody
      • Peroxisomal acyl coenzyme A oxidase 1 antibody
      • Peroxisomal acyl-coenzyme A oxidase 1 antibody
      • Peroxisomal fatty acyl CoA oxidase antibody
      • SCOX antibody
      • Straight chain acyl CoA oxidase antibody
      • Straight-chain acyl-CoA oxidase antibody
      see all

    图片

    • Western blot - ACOX1 antibody - Carboxyterminal end (ab71483)
      Western blot - ACOX1 antibody - Carboxyterminal end (ab71483)
      All lanes : Anti-ACOX1 antibody - C-terminal (ab71483) at 1/50 dilution

      Lane 1 : Non-transfected 293 cell lysates
      Lane 2 : ACOX1 (clone RB04652) transfected 293 cell lysates

      Lysates/proteins at 2 µg per lane.

      Predicted band size: 74 kDa
      Observed band size: 74 kDa

    实验方案

    文献

    ab71483 has not yet been referenced specifically in any publications.

    发表研究结果有使用 ab71483？请让我们知道，以便我们可以引用本数据表中的参考文章。

    客户评价及客户问答

    提交评价 提交问题

    There are currently no Customer reviews or Questions for ab71483.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    注册