Anti-ACOX1抗体- C-terminal (ab71483)

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概述

  • 产品名称
    Anti-ACOX1抗体- C-terminal
    参阅全部 ACOX1 一抗
  • 描述
    兔多克隆抗体to ACOX1 - C-terminal
  • 宿主
    Rabbit
  • 经测试应用
    适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    A KLH conjugated synthetic peptide selected from the C-terminal region of human ACOX1.

应用

Our Abpromise guarantee covers the use of ab71483 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/50 - 1/100. Detects a band of approximately 74 kDa (predicted molecular weight: 74 kDa).
ELISA 1/1000.

靶标

  • 功能
    Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. Isoform 1 shows highest activity against medium-chain fatty acyl-CoAs and activity decreases with increasing chain length. Isoform 2 is active against a much broader range of substrates and shows activity towards very long-chain acyl-CoAs. Isoform 2 is twice as active as isoform 1 against 16-hydroxy-palmitoyl-CoA and is 25% more active against 1,16-hexadecanodioyl-CoA.
  • 组织特异性
    Widely expressed with highest levels of isoform 1 and isoform 2 detected in testis. Isoform 1 is expressed at higher levels than isoform 2 in liver and kidney while isoform 2 levels are higher in brain, lung, muscle, white adipose tissue and testis. Levels are almost equal in heart.
  • 通路
    Lipid metabolism; peroxisomal fatty acid beta-oxidation.
  • 疾病相关
    Adrenoleukodystrophy, pseudoneonatal
  • 序列相似性
    Belongs to the acyl-CoA oxidase family.
  • 细胞定位
    Peroxisome.
  • Information by UniProt
  • 数据库链接
    • 别名
      • ACOX antibody
      • ACOX1 antibody
      • ACOX1_HUMAN antibody
      • Acyl CoA oxidase 1 palmitoyl antibody
      • Acyl CoA oxidase straight chain antibody
      • AOX antibody
      • EC 1.3.3.6 antibody
      • PALMCOX antibody
      • Palmitoyl CoA oxidase antibody
      • Palmitoyl-CoA oxidase antibody
      • Peroxisomal acyl coenzyme A oxidase 1 antibody
      • Peroxisomal acyl-coenzyme A oxidase 1 antibody
      • Peroxisomal fatty acyl CoA oxidase antibody
      • SCOX antibody
      • Straight chain acyl CoA oxidase antibody
      • Straight-chain acyl-CoA oxidase antibody
      see all

    图片

    • Western blot - Anti-ACOX1 antibody - C-terminal (ab71483)
      Western blot - Anti-ACOX1 antibody - C-terminal (ab71483)
      All lanes : Anti-ACOX1 antibody - C-terminal (ab71483) at 1/50 dilution

      Lane 1 : Non-transfected 293 cell lysates
      Lane 2 : ACOX1 (clone RB04652) transfected 293 cell lysates

      Lysates/proteins at 2 µg per lane.

      Predicted band size: 74 kDa
      Observed band size: 74 kDa

    实验方案

    文献

    ab71483 has not yet been referenced specifically in any publications.

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