Anti-Aconitase 1 (phospho S138)抗体(ab63260)

概述

  • 产品名称Anti-Aconitase 1 (phospho S138)抗体
    参阅全部 Aconitase 1 一抗
  • 描述
    兔多克隆抗体to Aconitase 1 (phospho S138)
  • 特异性ab63260 detects endogenous levels of Aconitase 1 only when phosphorylated at serine 138.
  • 经测试应用适用于: ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic phosphopeptide derived from human Aconitase 1 around the phosphorylation site of serine 138 (A-D-SP-L-Q).

  • 阳性对照
    • Human ovary tissue

性能

应用

Our Abpromise guarantee covers the use of ab63260 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/5000.
IHC-P 1/50 - 1/100.

靶标

  • 功能Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake, sequestration and utilization of iron when cellular iron levels are low. Binds to iron-responsive elements (IRES) in target mRNA species when iron levels are low. Binding of a 4Fe-4S cluster precludes RNA binding.
    Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
  • 序列相似性Belongs to the aconitase/IPM isomerase family.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ACO 1 antibody
    • ACO1 antibody
    • ACOC_HUMAN antibody
    • Aconitase 1 soluble antibody
    • Aconitase antibody
    • Aconitase1 antibody
    • Aconitate hydratase antibody
    • ACONS antibody
    • Citrate hydro lyase antibody
    • Citrate hydro-lyase antibody
    • Cytoplasmic aconitate hydratase antibody
    • Ferritin repressor protein antibody
    • IRE BP 1 antibody
    • IRE-BP 1 antibody
    • IREB 1 antibody
    • IREB1 antibody
    • IREBP antibody
    • IREBP1 antibody
    • Iron regulatory protein 1 antibody
    • Iron responsive element binding protein 1 antibody
    • Iron-responsive element-binding protein 1 antibody
    • IRP 1 antibody
    • IRP1 antibody
    • OTTHUMP00000045233 antibody
    see all

Anti-Aconitase 1 (phospho S138) antibody 图像

  • Immunohistochemical analysis of Aconitase 1 (phospho S138) expression in paraffin-embedded human ovary tissue using ab63260 at 1/50. Left image: untreated. Right image: sample treated with immunising phosphopeptide.

Anti-Aconitase 1 (phospho S138) antibody (ab63260)参考文献

ab63260 has not yet been referenced specifically in any publications.

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