概述

  • 产品名称
    Anti-Aconitase 1抗体
    参阅全部 Aconitase 1 一抗
  • 描述
    兔多克隆抗体to Aconitase 1
  • 特异性
    ab62701 detects endogenous levels of total Aconitase 1 protein.
  • 经测试应用
    适用于: ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic non phosphopeptide derived from human Aconitase 1 around the phosphorylation site of serine 711 (Y-G-SP-R-R).

  • 阳性对照
    • Human thyroid gland tissue.

性能

应用

Our Abpromise guarantee covers the use of ab62701 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
IHC-P
  • 应用说明
    ELISA: 1/20000.
    IHC-P: 1/50 - 1/100.

    ab62701 can detect both of unmodified form and Ser-711 phosphorylated form of Aconitase 1 protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake, sequestration and utilization of iron when cellular iron levels are low. Binds to iron-responsive elements (IRES) in target mRNA species when iron levels are low. Binding of a 4Fe-4S cluster precludes RNA binding.
      Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
    • 序列相似性
      Belongs to the aconitase/IPM isomerase family.
    • 细胞定位
      Cytoplasm.
    • Information by UniProt
    • 数据库链接
    • 别名
      • ACO 1 antibody
      • ACO1 antibody
      • ACOC_HUMAN antibody
      • Aconitase 1 soluble antibody
      • Aconitase antibody
      • Aconitase1 antibody
      • Aconitate hydratase antibody
      • ACONS antibody
      • Citrate hydro lyase antibody
      • Citrate hydro-lyase antibody
      • Cytoplasmic aconitate hydratase antibody
      • Ferritin repressor protein antibody
      • IRE BP 1 antibody
      • IRE-BP 1 antibody
      • IREB 1 antibody
      • IREB1 antibody
      • IREBP antibody
      • IREBP1 antibody
      • Iron regulatory protein 1 antibody
      • Iron responsive element binding protein 1 antibody
      • Iron-responsive element-binding protein 1 antibody
      • IRP 1 antibody
      • IRP1 antibody
      • OTTHUMP00000045233 antibody
      see all

    图片

    • ab62701, at 1/50 dilution, staining Aconitase 1 in paraffin embedded human thyroid gland tissue by Immunohistochemistry in the absence or presence of the immunising peptide.

    文献

    ab62701 has not yet been referenced specifically in any publications.

    客户评价及客户问答

    There are currently no Customer reviews or Questions for ab62701.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    注册