Anti-Aconitase 1抗体(ab106945)

概述

  • 产品名称Anti-Aconitase 1抗体
    参阅全部 Aconitase 1 一抗
  • 描述
    山羊多克隆抗体to Aconitase 1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Cow
  • 免疫原

    Synthetic peptide:

    QVDFNRRADSLQKNQ

    by a Cysteine residue linker, corresponding to internal sequence amino acids 129-143 of Human Aconitase 1 (NP_002188.1).

  • 阳性对照
    • Human liver lysate

性能

应用

Our Abpromise guarantee covers the use of ab106945 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 100 kDa (predicted molecular weight: 98 kDa).

靶标

  • 功能Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake, sequestration and utilization of iron when cellular iron levels are low. Binds to iron-responsive elements (IRES) in target mRNA species when iron levels are low. Binding of a 4Fe-4S cluster precludes RNA binding.
    Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
  • 序列相似性Belongs to the aconitase/IPM isomerase family.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ACO 1 antibody
    • ACO1 antibody
    • ACOC_HUMAN antibody
    • Aconitase 1 soluble antibody
    • Aconitase antibody
    • Aconitase1 antibody
    • Aconitate hydratase antibody
    • ACONS antibody
    • Citrate hydro lyase antibody
    • Citrate hydro-lyase antibody
    • Cytoplasmic aconitate hydratase antibody
    • Ferritin repressor protein antibody
    • IRE BP 1 antibody
    • IRE-BP 1 antibody
    • IREB 1 antibody
    • IREB1 antibody
    • IREBP antibody
    • IREBP1 antibody
    • Iron regulatory protein 1 antibody
    • Iron responsive element binding protein 1 antibody
    • Iron-responsive element-binding protein 1 antibody
    • IRP 1 antibody
    • IRP1 antibody
    • OTTHUMP00000045233 antibody
    see all

Anti-Aconitase 1 antibody 图像

  • Anti-Aconitase 1 antibody (ab106945) at 0.1 µg/ml + Human liver lysate in RIPA buffer at 35 µg
    Developed using the ECL technique

    Predicted band size : 98 kDa

Anti-Aconitase 1 antibody (ab106945)参考文献

ab106945 has not yet been referenced specifically in any publications.

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