概述

  • 产品名称Anti-Acinus抗体
    参阅全部 Acinus 一抗
  • 描述
    兔多克隆抗体to Acinus
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Dog, Pig, Xenopus laevis, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Xenopus tropicalis
  • 免疫原

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) corresponding to a region between residue 1291 and the C-terminus (residue 1341) of human Acinus (NP_055792.1)

  • 阳性对照
    • human basal cell carcinoma and human stomach adenocarcinoma tissue.

性能

应用

Our Abpromise guarantee covers the use of ab84454 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/100 - 1/500.

靶标

  • 功能Component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Induces apoptotic chromatin condensation after activation by CASP3.
  • 组织特异性Ubiquitous.
  • 序列相似性Contains 1 SAP domain.
  • 翻译后修饰Undergoes proteolytic cleavage; the processed form is active, contrary to the uncleaved form.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ACIN 1 antibody
    • ACIN1 antibody
    • ACINU_HUMAN antibody
    • Acinus antibody
    • ACN antibody
    • Apoptotic chromatin condensation inducer 1 antibody
    • Apoptotic chromatin condensation inducer in the nucleus antibody
    • DKFZp667N107 antibody
    • fSAP152 antibody
    • functional spliceosome-associated protein 152 antibody
    • KIAA0670 antibody
    see all

Anti-Acinus antibody 图像

  • ab84454, at 1/250 dilution, staining Acinus in formalin-fixed, paraffin-embedded stomach adenocarcinoma. by Immunohistochemistry, using DAB detection.
  • ab84454, at 1/250 dilution, staining Acinus in formalin-fixed, paraffin-embedded human basal cell carcinoma. by Immunohistochemistry, using DAB detection.

Anti-Acinus antibody (ab84454)参考文献

This product has been referenced in:
  • Singh SS  et al. Comparison of ACINUS, caspase-3, and TUNEL as apoptotic markers in determination of tumor growth rates of clinically localized prostate cancer using image analysis. Prostate 69:1603-10 (2009). IHC-P ; Human . Read more (PubMed: 19644955) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"