概述

  • 产品名称Anti-Acinus抗体[2005C3a]
    参阅全部 Acinus 一抗
  • 描述
    小鼠单克隆抗体[2005C3a] to Acinus
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant human Acinus fragment carrying 50-200 aa

  • 阳性对照
    • recombinant immunozing fragment

性能

应用

Our Abpromise guarantee covers the use of ab50827 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution. Detects a band of approximately 200 kDa (predicted molecular weight: 152 kDa).

靶标

  • 功能Component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Induces apoptotic chromatin condensation after activation by CASP3.
  • 组织特异性Ubiquitous.
  • 序列相似性Contains 1 SAP domain.
  • 翻译后修饰Undergoes proteolytic cleavage; the processed form is active, contrary to the uncleaved form.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ACIN 1 antibody
    • ACIN1 antibody
    • ACINU_HUMAN antibody
    • Acinus antibody
    • ACN antibody
    • Apoptotic chromatin condensation inducer 1 antibody
    • Apoptotic chromatin condensation inducer in the nucleus antibody
    • DKFZp667N107 antibody
    • fSAP152 antibody
    • functional spliceosome-associated protein 152 antibody
    • KIAA0670 antibody
    see all

Anti-Acinus antibody [2005C3a] 图像

  • Anti-Acinus antibody [2005C3a] (ab50827) at 1/50 dilution + A2058 whole cell lysate at 50 µg

    Secondary
    anti-mouse IgG at 1/2500 dilution

    Predicted band size : 152 kDa

Anti-Acinus antibody [2005C3a] (ab50827)参考文献

This product has been referenced in:
  • Huang Y  et al. Global tumor protein p53/p63 interactome: Making a case for cisplatin chemoresistance. Cell Cycle 11:2367-79 (2012). WB ; Human . Read more (PubMed: 22672905) »

See 1 Publication for this product

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