概述

  • 产品名称Anti-ACADM抗体
    参阅全部 ACADM 一抗
  • 描述
    小鼠多克隆抗体to ACADM
  • 经测试应用适用于: WB, ICC/IF, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length Human ACADM (NP_000007.1)

  • 阳性对照
    • Human liver or HepG2 cell lysate. Human kidney tissue. HeLa cells. Transfected 293T cell line

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应用

Our Abpromise guarantee covers the use of ab88507 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 46 kDa.
ICC/IF Use a concentration of 10 µg/ml.
IHC-P Use a concentration of 3 µg/ml.

靶标

  • 功能This enzyme is specific for acyl chain lengths of 4 to 16.
  • 通路Lipid metabolism; mitochondrial fatty acid beta-oxidation.
  • 疾病相关Defects in ACADM are the cause of acyl-CoA dehydrogenase medium-chain deficiency (ACADMD) [MIM:201450]. It is an autosomal recessive disease which causes fasting hypoglycemia, hepatic dysfunction, and encephalopathy, often resulting in death in infancy.
  • 序列相似性Belongs to the acyl-CoA dehydrogenase family.
  • 细胞定位Mitochondrion matrix.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ACAD 1 antibody
    • ACAD1 antibody
    • Acadm antibody
    • ACADM_HUMAN antibody
    • Acyl coenzyme A dehydrogenase antibody
    • Acyl coenzyme A dehydrogenase C 4 to C 12 straight chain antibody
    • FLJ18227 antibody
    • FLJ93013 antibody
    • FLJ99884 antibody
    • MCAD antibody
    • MCADH antibody
    • Medium chain acyl CoA dehydrogenase antibody
    • Medium chain fatty acyl CoA dehydrogenase antibody
    • Medium chain specific acyl CoA dehydrogenase antibody
    • Medium chain specific acyl CoA dehydrogenase mitochondrial antibody
    • Medium-chain specific acyl-CoA dehydrogenase antibody
    • mitochondrial antibody
    see all

Anti-ACADM antibody 图像

  • Anti-ACADM antibody (ab88507) at 1 µg/ml + Human liver lysate at 50 µg/ml

    Predicted band size : 46 kDa
    Observed band size : 40 kDa (why is the actual band size different from the predicted?)
  • Anti-ACADM antibody (ab88507) at 1 µg/ml + HepG2 cell lysate at 50 µg

    Predicted band size : 46 kDa
    Observed band size : 40 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-ACADM antibody (ab88507) at 1 µg/ml

    Lane 1 : transfected 293T cell lysate
    Lane 2 : untransfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 46 kDa
    Observed band size : 46 kDa
    Additional bands at : 24 kDa. We are unsure as to the identity of these extra bands.
  • Purified ab88507 at 3ug/ml staining ACADM in formailn-fixed, paraffin-embedded Human kidney tissue.
  • Purified ab88507 at 10ug/ml staining ACADM in HeLa cells by immunofluorescence.

Anti-ACADM antibody (ab88507)参考文献

ab88507 has not yet been referenced specifically in any publications.

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