概述

  • 产品名称Anti-ACAD8抗体
    参阅全部 ACAD8 一抗
  • 描述
    兔多克隆抗体to ACAD8
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Cow
  • 免疫原

    Recombinant fragment, corresponding to a region within amino acids 146-411 of Human ACAD8 (NP_055199).

  • 阳性对照
    • 293T whole cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab96567 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 45 kDa.

靶标

  • 功能Has very high activity toward isobutyryl-CoA. Is an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Plays a role in transcriptional coactivation within the ARC complex.
  • 组织特异性Detected at comparable levels in all tissues examined (heart, lung, brain, skeletal muscle, pancreas and placenta). Weakly expressed in liver and kidney.
  • 通路Amino-acid degradation; L-valine degradation.
  • 疾病相关Defects in ACAD8 are the cause of isobutyryl-CoA dehydrogenase deficiency (IBDD) [MIM:611283]. The symptoms of IBDD generally appear until late in infancy or in childhood and can include poor feeding and growth (failure to thrive), a weakened and enlarged heart (dilated cardiomyopathy), seizures, and low numbers of red blood cells (anemia).
  • 序列相似性Belongs to the acyl-CoA dehydrogenase family.
  • 细胞定位Mitochondrion.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ACAD 8 antibody
    • ACAD-8 antibody
    • ACAD8 antibody
    • ACAD8_HUMAN antibody
    • Activator-recruited cofactor 42 kDa component antibody
    • Acyl CoA dehydrogenase family member 8 antibody
    • Acyl Coenzyme A dehydrogenase family member 8 antibody
    • Acyl-CoA dehydrogenase family member 8 antibody
    • ARC42 antibody
    • FLJ22590 antibody
    • IBD antibody
    • Isobutyryl-CoA dehydrogenase antibody
    • Isobutyryl-CoA dehydrogenase, mitochondrial antibody
    • mitochondrial antibody
    see all

Anti-ACAD8 antibody 图像

  • Anti-ACAD8 antibody (ab96567) at 1/500 dilution + 293T whole cell lysate at 30 µg

    Predicted band size : 45 kDa

Anti-ACAD8 antibody (ab96567)参考文献

ab96567 has not yet been referenced specifically in any publications.

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