Ac-TVASSSTA Octapeptide多肽(ab95132)
Key features and details
- Purity: > 85% HPLC
- Suitable for: MS, Functional Studies
描述
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产品名称
Ac-TVASSSTA Octapeptide多肽 -
纯度
> 85 % HPLC. -
无动物成分
No -
性质
Synthetic
技术指标
Our Abpromise guarantee covers the use of ab95132 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
Mass Spectrometry
Functional Studies
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形式
Lyophilized -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 7.40
Constituents: 2.38% HEPES, 0.58% Sodium chloride -
复溶Hydrate in 0.5ml of H2O.
常规信息
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相关性
Ac-TVASSSTA is an Octapeptide mimic of the N-terminal residues of the reactive center loop of PAI-1 (cf. P14-P7 residues). The Octapeptide inactivates PAI-1 by substituting for strand 4 in beta-sheet A in a manner that competes with formation of the latent species. Insertion of the peptide into beta-sheet A effectively forms a stable complex that converts PAI-1 into a substrate for tissue-type plasminogen activator (tPA) and other target proteinases. The resulting species of PAI-1 is thermodynamically stable and is useful for investigating the role of reactive center loop insertion.
图片
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Mass spectrometry analysis of ab95132
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HPLC analysis of ab95132
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10% SDS-PAGE Reduced
Lane 1: PAI-1 (5 ug) Frozen Lane 2: PAI-1 (5 ug) Incubated
Lane 3: PAI-1 (5 ug) + ab95132 (3 ug) Incubated Lane 4: PAI-1 (5 ug) Frozen + tPA (0.07 ug)
Lane 5: PAI-1 (5 ug) Incubated + tPA (0.07 ug) Lane 6: PAI-1 (5 ug) + ab95132 (3 ug) Incubated + tPA (0.07 ug)
Lane 7: Molecular weight markers
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (0)
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