功能Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function.
组织特异性Placenta and kidney.
序列相似性Belongs to the copper/topaquinone oxidase family.
翻译后修饰Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.