概述

  • 产品名称Anti-ABI2抗体
    参阅全部 ABI2 一抗
  • 描述
    兔多克隆抗体to ABI2
  • 经测试应用适用于: WB, IPmore details
  • 种属反应性
    与反应: Human
    预测可用于: Gorilla, Opossum, Orangutan, Bat, Elephant
  • 免疫原

    Synthetic peptide, corresponding to a region within internal sequence amino acids 351-401 of Human ABI2 (NP_005750.4).

  • 阳性对照
    • Whole cell lysate from HeLa cells

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.09% Sodium azide
    Constituent: 99% Tris citrate/phosphate
    Note: pH 7 to 8
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab113991 was affinity purified using an epitope specific to ABI2 immobilized on solid support.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab113991 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/5000. Predicted molecular weight: 56 kDa.
IP Use at 2-5 µg/mg of lysate.

靶标

  • 功能May act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Regulates ABL1/c-Abl-mediated phosphorylation of MENA.
  • 序列相似性Belongs to the ABI family.
    Contains 1 SH3 domain.
    Contains 1 t-SNARE coiled-coil homology domain.
  • 翻译后修饰Is a substrate for ABL1.
  • 细胞定位Cytoplasm and Cell projection > lamellipodium. Cell projection > filopodium. Cytoplasm > cytoskeleton. Isoform 1 but not isoform 3 is localized to protruding lamellipodia and filopodia tips.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Abelson interactor 2 antibody
    • ABI 2 antibody
    • Abi-2 antibody
    • ABI2 antibody
    • ABI2_HUMAN antibody
    • ABI2B antibody
    • Abl binding protein 3 antibody
    • Abl interacting protein 1 (SH3 containing protein) antibody
    • Abl interactor 2 antibody
    • Abl interactor protein 2b antibody
    • Abl-binding protein 3 antibody
    • AblBP3 antibody
    • AIP 1 antibody
    • Arg binding protein 1 antibody
    • Arg protein tyrosine kinase binding protein antibody
    • Arg-binding protein 1 antibody
    • ArgBP1 antibody
    • ARGBPIA antibody
    • ArgBPIB antibody
    • OTTHUMP00000163783 antibody
    • OTTHUMP00000163784 antibody
    • OTTHUMP00000206182 antibody
    • OTTHUMP00000206183 antibody
    • OTTHUMP00000206184 antibody
    • OTTHUMP00000206185 antibody
    • SSH3BP2 antibody
    see all

Anti-ABI2 antibody 图像

  • All lanes : Anti-ABI2 antibody (ab113991) at 0.4 µg/ml

    Lane 1 : HeLa whole cell lysate at 50 µg
    Lane 2 : HeLa whole cell lysate at 15 µg
    Lane 3 : HeLa whole cell lysate at 5 µg

    Developed using the ECL technique

    Predicted band size : 56 kDa


    Exposure time : 30 seconds
  • ab113991, at 1 µg/ml, detecting ABI2 by WB following immunoprecipitation.
    Lane 1: IP using a rabbit anti-ABI2 which recognizes an upstream epitope
    Lane 2: IP using ab113991
    Lane 3; IP using control IgG.
    ab113991 was used for immunoprecipitation at 3 µg/mg of HeLa whole cell lysate. 1 mg of lysate was used for IP and 20% of IP was loaded.
    Detection: Chemiluminescence with a 3 minute exposure time.

Anti-ABI2 antibody (ab113991)参考文献

ab113991 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab113991.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"