概述

  • 产品名称Anti-ABHD12抗体
    参阅全部 ABHD12 一抗
  • 描述
    山羊多克隆抗体to ABHD12
  • 特异性ab81906 is expected to recognize isoform a (NP_001035937.1) only.
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Mouse, Rat
    预测可用于: Human, Cynomolgus Monkey
  • 免疫原

    Synthetic peptide:

    C-REFLGKSEPEHQH

    , corresponding to C terminal amino acids 386-398 of Human ABHD12 (NP_001035937.1).

  • 阳性对照
    • Mouse Brain and Rat Brain lysates.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris saline, pH 7.3
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab81906 is purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • 克隆多克隆
  • 同种型IgG

应用

Our Abpromise guarantee covers the use of ab81906 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明Peptide ELISA: Antibody detection limit dilution 1/32000.
    WB: Use at a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 40 kDa (predicted molecular weight: 45 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Has 2-arachidonoylglycerol hydrolase activity (By similarity). May be a regulator of endocannabinoid signaling pathways.
    • 疾病相关Defects in ABHD12 are the cause of polyneuropathy hearing loss ataxia retinitis pigmentosa and cataract (PHARC) [MIM:612674]. PHARC is a slowly progressive neurologic disorder with a variable phenotype resembling Refsum disease. Clinical features include sensorineural hearing loss, visual problems related to cataracts, retinitis pigmentosa, pes cavus, ataxic and/or spastic gait disturbances with a progressive sensorimotor peripheral neuropathy. Other features include hyporeflexia, hyperreflexia, extensor plantar responses.
    • 序列相似性Belongs to the serine esterase family.
    • 翻译后修饰Glycosylated.
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 2-arachidonoylglycerol hydrolase antibody
      • 6330583M11Rik antibody
      • ABD12_HUMAN antibody
      • ABHD12 antibody
      • ABHD12A antibody
      • Abhydrolase domain containing protein 12 antibody
      • Abhydrolase domain-containing protein 12 antibody
      • AI431047 antibody
      • AW547313 antibody
      • BEM46L2 antibody
      • C20orf22 antibody
      • Monoacylglycerol lipase ABHD12 antibody
      • RP23-241M12.2 antibody
      see all

    Anti-ABHD12 antibody 图像

    Anti-ABHD12 antibody (ab81906)参考文献

    ab81906 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"