概述

  • 产品名称Anti-ABCC11抗体
    参阅全部 ABCC11 一抗
  • 描述
    兔多克隆抗体to ABCC11
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Saccharomyces cerevisiae
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 1295-1344 (NSKIILIDEA TASIDMETDT LIQRTIREAF QGCTVLVIAH RVTTVLNCDH) of Human ABCC11 (NP_149163).

  • 阳性对照
    • NCI-H226 cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab98979 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 154 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 相关性ABCC11 belongs to the ABC transporter family, conjugate transporter (TC 3.A.1.208) subfamily. It contains two ABC transmembrane type-1 domains and two ABC transporter domains. ABCC11 participates in physiological processes involving bile acids, conjugated steroids and cyclic nucleotides and enhances the cellular extrusion of cAMP and cGMP. It also stimulates the ATP-dependent uptake of a range of physiological and synthetic lipophilic anions, including the glutathione S-conjugates leukotriene C4 and dinitrophenyl S-glutathione, steroid sulfates such as dehydroepiandrosterone 3-sulfate (DHEAS) and estrone 3-sulfate, glucuronides such as estradiol 17-beta-D-glucuronide (E(2)17betaG), the monoanionic bile acids glycocholate and taurocholate, and methotrexate. It probably functions to secrete earwax.
  • 细胞定位Membrane; Multi-pass membrane protein.
  • 数据库链接
  • 别名
    • ABCC 11 antibody
    • ATP binding cassette protein C11 antibody
    • ATP binding cassette sub family C (CFTR/MRP) member 11 antibody
    • ATP binding cassette sub family C member 11 antibody
    • ATP binding cassette transporter MRP8 antibody
    • ATP binding cassette transporter sub family C member 11 antibody
    • EWWD antibody
    • MRP8 antibody
    • Multi resistance protein 8 antibody
    • Multidrug resistance associated protein 8 antibody
    • OTTHUMP00000164191 antibody
    • WW antibody
    see all

Anti-ABCC11 antibody 图像

  • Anti-ABCC11 antibody (ab98979) at 1 µg/ml + NCI-H226 cell lysate at 10 µg

    Predicted band size : 154 kDa

Anti-ABCC11 antibody (ab98979)参考文献

ab98979 has not yet been referenced specifically in any publications.

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